摘要
本文报道在两相溶剂体系中利用木瓜蛋白酶催化合成Aspartame前体Z－APM的研究。实验结果表明，木瓜蛋白酶在水-正丁醇两相体系具有较好的催化活性，在底物比（Z－L－Asp：L－PheOMe）为1：1，温度37℃条件下连续反应72h，Z－APM的产率可达62．8％。
Papain-catalyzed synthesis of aspartame precursor Z-APM in biphasic solvent system wasinvestigated. Z-APM was obtained in the yield of 62.8% under mole ratio of substrates 1:1, temperature37℃ and reaction time 72h. The result shows that the catalytic activity of papain in n-BuOH-H2O wasbetter than in other organic solvent-H2O systems.
出处
《高校化学工程学报》
EI
CAS
CSCD
北大核心
1999年第4期382-385,共4页
Journal of Chemical Engineering of Chinese Universities
