摘要
目的探讨肝硬化并上消化道出血(UGH)患者预后的影响因素。方法 回顾性分析2003年6月至2009年6月我科196例肝硬化并UGH患者的临床资料。根据患者预后分为生存组与死亡组,比较两组病例的出血病因、既往出血史、24h内再出血、肝功能Child-Pugh分级、并发症(腹水、肝性脑病、肝肾综合征)、血常规(PLT、Hb)、重要生化指标(TBIL、ALB、Cr)及凝血相关指标(PT、TT、aPTT)等因素。结果 死亡组出血原因中食管胃静脉曲张出血发生率高于生存组,门脉高压性胃病出血发生率低于生存组(P<0.01);两组在上述其他观察指标间差异均有统计学意义(P<0.05,P<0.01)。结论 出血病因、既往出血史、24h内再出血、肝功能分级、并发症、重要生化指标(PLT、Hb、TBIL、ALB、Cr)及凝血因子水平均影响肝硬化并上消化道出血患者的转归,可作为评价此病预后的重要指标。
Objective To explore the influencing factors of prognsis on patients with upper gastrointestinal hemorrhage（UGH） induced by cirrhosis.Methods The clinical date of 196 cases with UGH induced by cirrhosis from June 2003 to June 2009 were retrospectively analyzed.Cases were divided into survival group and dead group according to their prognosis,and the predisposing factors of the two groups which included the hemorrhage causes,UGH history,rebleeding within 24 hours,Child-Pugh grade,complications（ascites,hepatic encephalopathy,hepatorenal syndrome）,blood routine（PLT,Hb）,important biochemical parameters（TBIL,ALB,Cr） and coagulation-related indicators（PT,TT,aPTT） were compared.Results Of bleeding causes,the dead group was higher in esophageal variceal bleeding and less in portal hypertensive gastropathy bleeding than the survival group（P0.01）.There were signficant differces in above other observing parameters between the two groups（P0.05,P0.01）.Conclusion The hemorrhage causes,UGH history,rebleeding within 24 hours,liver function grade,complications,important parameters（PLT,Hb,TBIL,ALB,Cr） and coagulation factors level could influence survival rate of cirrhosis complicated with UGH and be used as important indicators to determine prognsis of the disease.
出处
《临床消化病杂志》
2011年第1期43-45,共3页
Chinese Journal of Clinical Gastroenterology
关键词
肝硬化
上消化道出血
预后
影响因素
Cirrhosis
Upper gastrointestinal hemorrhage
Prognosis
influence factors
