摘要
目的探讨阿奇霉素联合红霉素治疗小儿支原体肺炎的临床疗效。方法本样本回顾分析2009年1月～2010年6月住院治疗的80例支原体肺炎患儿的临床资料,未选择合并其他感染的病例。按随机原则分为观察组和对照组各40例。结果观察组总有效率97.5%明显高于对照组80.0%。观察组平均退热时间明显低于对照组,差异有统计学意义(t=2.2086,P<0.05);平均止咳时间明显低于对照组,差异有统计学意义(t=2.2577,P<0.05);平均住院天数明显低于对照组,差异有统计学意义(t=2.1629,P<0.05)。观察组有8例(20.0%)发生恶心、呕吐等胃肠道症状,对照组有6例(15.0%)出现恶心、呕吐等胃肠道症状,均能耐受,未停药。两周后复查肝肾功能,轻度肝损害观察组、对照组均有2例(5.0%),停药后均恢复正常,无明显统计学差异(x2=0.29,P>0.05)。结论阿奇霉素联合红霉素治疗小儿支原体肺炎,可较快改善临床症状,治疗效果优于单用阿奇霉素序贯疗法,患儿依从性好,值得临床进一步推广使用。
Objective To explore the erythromycin and azithromycin treat children mycoplasma pneumonia clinical efficacy.Methods Retrospective analysis of the samples from January 2009 to June 2010 80 cases of hospitalized children with mycoplasma pneumonia clinical data,Combined with other infections is not selected.Results The total effective observation group was 97.5% higher than the control group was 80.0%,The average cooling time of the observation group was significantly lower than the control group,Significant difference （t = 2.1629,P 0.05）.Observation group,8 patients （20.0%）,nausea,vomiting and other gastrointestinal symptoms,Well tolerated,No withdrawal.Control group,6 cases （15.0%） nausea,vomiting and other gastrointestinal symptoms.Liver and kidney function two weeks after the review,Mild liver damage observation group and control group were 2 cases （5.0%）,No significant difference （x2 = 0.29,P 0.05）.Conclusion Azithromycin and Erythromycin treat the children mycoplasma pneumonia,can quickly improve the clinical symptoms,Better than single treatment with azithromycin sequential therapy,Children with good compliance,it is worth to further promote the use of clinical.
出处
《当代医学》
2011年第10期56-57,共2页
Contemporary Medicine
关键词
阿奇霉素
红霉素
小儿
支原体肺炎
Azithromycin
Erythromycin
Children
Mycoplasma pneumonia
