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老年重症肺炎患者的抗菌药物降阶梯治疗策略与利奈唑胺的临床应用 被引量:7

Deescalation therapy of antibiotic drugs for elderly patients with severe nosocomial pneumonia and clinical using of linezolid
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摘要 目的使用降阶梯方案治疗呼吸科重症监护病房(RICU)老年重症肺炎患者并评价其疗效。方法回顾性分析我院2009年11月至2010年11月RICU老年重症肺炎患者40例,分成传统治疗组和降阶梯治疗组,比较两组患者的初始治疗恰当率、感染控制率和感染控制所需时间等指标。结果降阶梯治疗组与传统治疗组的初始治疗恰当率分别为82.5%与50.5%,差异有统计学意义(P<0.05);治疗有效率分别为85.5%、50.0%,差异有统计学意义(P<0.05);感染控制所需天数分别为71、2 d,差异有统计学意义(P<0.05)。结论对于RICU老年重症肺炎患者,使用降阶梯治疗可获得良好疗效。 Objective To use deescalation therapy for the patients with severe nosocomial pneumonia in the RICU,and evaluate the curative effect.Methods Forty patients with severe nosocomial pneumonia from Nov.2009 to Nov.2010 were divided into two groups(traditional group and deescalation group).Their adequate rate of initial therapy,infection controlled rate and the days from the on-set of treatment to the infection controlled were compared.Results Between deescalation group and traditional group,the adequate rate of initial therapy was 82.5% vs 50.5%(P0.05),respectively.The infection controlled rate was 85.5% vs 50.0%(P0.05),respectively.The days from the onset of treatment to the infection controlled were 7 vs 12 days(P0.05),respectively.Conclusion Deescalation therapy in RICU for treating severe nosocomial pneumonia has better curative effect.
出处 《临床医学》 CAS 2011年第3期25-27,共3页 Clinical Medicine
关键词 降阶梯治疗 呼吸科重症监护病房 重症肺炎 利奈唑胺 Deescalation therapy Respiratory intensive care unit Severe pneumonia Linezolid
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