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纤溶系统与颈动脉粥样硬化关系的研究 被引量:2

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摘要 目的研究纤溶系统与不同性质、程度颈动脉粥样硬化的关系。方法将2006年1至12月住院的70例患者依颈动脉超声结果分为颈AS组40例和对照组30例,并将颈AS组40例依颈AS不同性质、程度再进行分组,对试验对象进行t-PA及PAI-1含量检查。结果不同程度狭窄颈AS组与对照组相比,PAI-1及t-PA含量显著增高(P﹤0.01)。颈ASⅠ级与颈ASⅡ级患者的PAI-1及t-PA含量相比差异无统计学意义(P﹥0.05)。与IMT组相比,颈动脉斑块组PAI-1及t-PA含量显著增高(P﹤0.01),不稳定斑块与稳定斑块组间的PAI-1及t-PA含量差异无统计学意义(P﹥0.05)。结论颈动脉粥样斑块患者较单纯颈动脉内膜增厚患者纤溶活性有降低。
出处 《河北医药》 CAS 2011年第6期851-853,共3页 Hebei Medical Journal
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