摘要
目的:探讨A型肉毒毒素治疗Mei ge综合征的方法及疗效。方法:47例患者在肌电图引导下用兼作注射器的针电极进行,在患者肌痉挛部位用A型肉毒毒素肌肉内注射,每点注射量为0.1～0.2ml(含肉毒毒素2.5～5 U),注射点数为数点～8点。根据Cohen、Albert痉挛强度分级评估疗效。结果:注射后一般3～4天起效,疗效持续3～6个月,复发者重复注射仍有效。治疗后患者肌痉挛强度明显下降,与治疗前比较有极显著性差异(P<0.01);症状完全缓解和明显缓解者达89.4%,治疗前后疗效比较有极显著性差异(P<0.01)。不良反应主要有:局部水肿、咬肌无力、眼睑下垂等,一般两周内均能恢复。结论:局部注射A型肉毒毒素治疗Meige综合征为一种安全有效、简便易行的治疗手段。
Objective Discusses botulinum toxin type A treatment of Meige syndrome the method and the effect.Methods 47 patients under the guidance of the EMG needle electrode with a double as the syringe,Spasm sites in patients with botulinum toxin type A intramuscular injection,each injected volume 0.1～0.2ml（including botulinum toxin 2.5～5U）,number of injection points to 8 points points.According to Cohen,Albert spasm intensity grading evaluation curative effect.Results After the injection,the general 3～4days of effect,the curative effect continued for 3～6 months,the recrudescence duplicate injection was still effective,After the treatment,the patient myospasm intensity obvious drop,the comparison has the extremely significance difference before the treatment（P0.01）.The symptom alleviates and the obvious alleviation completely reaches 89.4%,around the treatment the curative effect comparison has the extremely significance difference（P0.01）.Adverse reactions are mainly： local edema,bite muscle weakness,ptosis and so on,generally all can recover within two weeks.Conclusions Local injection of botulinum toxin type A treatment of Meige syndrome is a safe and effective and feasible treatment.
出处
《中国美容医学》
CAS
2011年第2期191-193,共3页
Chinese Journal of Aesthetic Medicine
