摘要
目的总结流行性乙型脑炎(乙脑)迟发型脑病的临床特点。方法回顾性调查2009年7—9月我院收治的18例发生迟发型脑病的乙脑患者(迟发脑病组)的流行病学及临床资料,与同期收治的34例未发生迟发型脑病的乙脑患者(非迟发脑病组)资料进行对比,探讨迟发型脑病的特点。结果 52例乙脑患者中18例(34%)发生迟发型脑病。2组的性别、极期的临床表现、外周血白细胞计数的差异无统计学意义,但患者年龄、脑脊液细胞数和脑影像学表现在2组间的差异有统计学意义。结论迟发脑病组的发病年龄为5～10岁,昏迷时间为第2～4病日,其脑脊液细胞数多为8～20/mm3,脑部影像学显示的病变范围较非迟发脑病组多。
Objective To summarize clinical features of late-onset encephalopathy in patients with epidemic encephalitis B. Methods A retrospective survey was conducted on the epidemiological and clinical data of 52 patients with epidemic encephalitis B treated in our hospital from Jul. to Sept. 2009, 18 with late-onset encephalopathy （late-onset encephalopathy group） and 34 without late-onset encephalopathy （non late-onset encephalopathy group）. The 2 groups were compared to investigate the characteristics of late-onset encephalopathy. Results Of 52 patients with epidemic encephalitis B, 18 （34%） developed late-onset encephalopathy. The sex, clinical manifestations and white blood cell counts were not significantly different, and the age, cell counts in cere- brospinal fluid and cerebral imaging findings were significantly different between the 2 groups. Conclusions In late-onset ence- phalopathy group, the onset age ranges from 5 to 10 years old, coma occurs during the 2nd-4th days, and the cell count in cerebrospinal fluid is 8-20 cells/mm^3. Cerebral imaging findings show a larger range of lesions in late-onset encephalopathy group than that in non late-onset encephalopathy group.
出处
《传染病信息》
2011年第1期34-36,共3页
Infectious Disease Information
关键词
脑炎
虫媒病毒
缺氧缺血
脑
治疗结果
encephalitis, arbovirus
hypoxia-ischemia, brain
treatment outcome
