摘要
目的:探讨Fisher判别模式对孤立性肺结节(SPN)CT鉴别诊断的应用价值。方法:回顾性分析149例SPN患者的CT资料,按病理及随访结果分为良性组和恶性组,对结节主要CT形态学特征进行评价,以两组间有统计学意义的形态学征象为判别指标并行Fisher判别,采用交叉核实法估计误判概率。结果:孤立性肺结节CT征象的Fisher判别公式为Z=-0.418X1+0.446X2-0.475X3+0.159X4+0.438X5-0.062X6+0.296X7+0.317X8+0.416X9,误判率为9.4%,敏感度为93.33%,特异度为84.09%,鉴别诊断的准确率达90.6%。结论:Fisher判别模式能够有效的对SPN进行鉴别诊断,具有较高的临床实用价值。
Objective：To assess the differential diagnostic value of Fisher discriminant in analyzing morphological features of solitary pulmonary nodule（SPN） by spiral CT scanning.Methods：This study included 149 cases of SPN,their morphological features by CT scanning were analyzed retrospectively,benign and malignant groups were classified according to pathological results after surgery or biopsy.The CT features were evaluated and Fisher discriminant was applied to the parameters with significant difference.Cross validation method was used for estimating the rate of miscarriage of justice.Results：The formula of Fisher discriminant was Z=-0.418X1＋0.446X2-0.475X3＋0.159X4＋0.438X5-0.062X6＋0.296X7＋0.317X8＋0.416X9,the rate of miscarriage of justice based on morphological features was 9.4%,the sensitivity and specificity were 93.33% and 84.09% respectively,the accuracy of differential diagnose was 90.6%.Conclusion：Fisher discriminant mode can make differential diagnosis of SPN effectively,having a high value in clinical experience.
出处
《放射学实践》
北大核心
2011年第2期180-182,共3页
Radiologic Practice
