摘要
目的 观察健康老年人戒烟１０ 年后肺功能的１０ 年变化。方法 ５１ 名戒烟１０ 年以上的健康老年人为研究对象，并挑选条件相同的从不吸烟健康老年人１２ 名作为随访对照，肺功能检查按常规方法进行。结果 戒烟１０ 年后健康老年人在随访的１０ 年中肺功能与从不吸烟健康老年人肺功能相比，肺活量（ＶＣ）、用力肺活量（ＦＶＣ） 、一秒钟用力呼气容积（ＦＥＶ１） 年下降值差异有显著性（Ｐ＜０－０１）；呼气峰流速（ＰＥＦ）年下降值差异有显著性（Ｐ＜０－０５）；残气量（ＲＶ）、残气量／肺总量（ＲＶ／ＴＬＣ）的年增加值差异有显著性（ Ｐ＜０－０１） 。一秒钟用力呼气容积与用力肺活量比值（ＦＥＶ１／ＦＶＣ） 、最大通气量（ＭＶＶ） 、最大呼气中期流量（ＭＭＥＦ）、功能残气量（ＦＲＣ）、肺总量（ＴＬＣ） 也有一定的改变，但变化值未达到统计学意义。结论 通过随访研究发现即使戒烟后曾吸烟对肺功能仍然存在一定影响，可能与研究对象吸烟时间长，吸烟量大所形成某些不可逆病理变化有关，并建议吸烟者应尽早戒烟。
Objective To observe changes of lung function for 10 years in healthy elderly ex smokers who have quitted smoking for more than 10 years Methods 51 healthy elderly ex smokers were selected and routine lung function tests were performed, 12 subjects, who have never smoked and all other criteria were similar, were chosen as controls Their routine lung function tests have also been followed up for 10 years Results The decrease of VC, FVC, FEV 1 and PEF of ex smokers were significantly lower than non smokers, the increase of RV and RV/TLC were significantly higher than non smokers FEV 1/FVC, MVV, MMEF, FRC and TLC were also different, however, the difference has not reached statistically significant Conclusions The influence of smoking could be prolonged, even the subject has stopped smoking for years, so we suggested to stop smoking the early the better
出处
《中华结核和呼吸杂志》
CAS
CSCD
北大核心
1999年第11期677-679,共3页
Chinese Journal of Tuberculosis and Respiratory Diseases
关键词
老年人
戒烟者
肺功能
随访研究
Healthy elder Ex smoker Lung functions Follow up
