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非小细胞肺癌化疗的个体化

Individual chemotherapy of non-small cell lung cancer
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摘要 个体化治疗是当前非小细胞肺癌的发展趋势,但什么是个体化治疗,为什么要进行个体化治疗,哪些标志物可以用以指导个体化治疗以及如何在非小细胞肺癌中实施个体化治疗是面临的主要问题。文章对上述问题进行了阐述。 Individual therapy is the current trend of treatment in non-small cell lung cancer patient. However, we still face many questions such as what is the individual therapy, why we need individual therapy, which biomarker could be used to guide the individual therapy and how to undergo individual therapy in nonsmall cell lung cancer patient. This article will give a review to answer these questions.
作者 周彩存
出处 《肿瘤研究与临床》 CAS 2010年第12期793-797,共5页 Cancer Research and Clinic
关键词 非小细胞肺 药物疗法 联合 个体化 Carcinoma, non-small-cell lung Drug therapy, combination Individual
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参考文献20

  • 1Eberhard DA,Johnson BE,Amler LC,et al.Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib.J Clin Oncol,2005,23:5900-5909.
  • 2Zheng Z,Chen T,Li X,et al.DNA synthesis and repair genes RRM1 and ERCC1 in lung cancer.N Engl J Med,2007,356:800-808.
  • 3Schettino C,Bareschino MA,Maione P,et al.The potential role of pharmacogenomic and genomic in the adjuvant treatment of early stage non small cell lung cancer.Curr Genomics,2008,9:252-262.
  • 4Cobo M,Massuti B,Morán T,et al.Spanish customized adjuvant trial (SCAT) based on BRCA1 mRNA levels.J Clin Oncol,2008,26(suppl):abstr 7533.
  • 5Kwiatkowski DJ,Harpole DH,Godleski J,et al.Prognostic factor analysis of 250 stage Ⅰ NSCLC patients:pathologic features are more important than molecular analyses.J Clin Oncol,1997,(suppl):abstr 1644.
  • 6Taron M,Cobo M,Isla D,et al.Role of ERCC1,XRCC3,Aurora A and TGFBR1 single-nucleotide polymorphisms (SNP) and CHFR and 14-3-3 σ methylation in a customized cisplatin (cis) trial based on ERCC1 mRNA levels in stage Ⅳ non-small cell lung cancer (NSCLC)patients (pts).J Clin Oncol,2007,25:7687a.
  • 7Taron M,Alberola V,Lopez Vivanco G,et al.Excision crosscomplementing group 1 (ERCC1) single nucleotide polymorphisms (SNPs) and survival in cisplatin (cis)/docetaxel (doc)-treated stage Ⅳ non-small cell lung cancer (NSCLC) patients (p):A Spanish Lung Cancer Group study.J Clin Oncol,2006,24:7053a.
  • 8de las Peias R,Sanchez-Ronco M,Alberola V,et al.Polymorphisms in DNA repair genes modulate survival in cisplatin/gemcitabinetreated non-small-cell lung cancer patients.Ann Oncol,2006,17:668-675.
  • 9Etxaniz O,Provencio M,Terrasa J,et al.Excision repair cross complementing 6 (ERCC6) single nucleotide polymorphism (SNP) and outcome to gemcitabine (gem)/cisplatin (cis) or docetaxel (doc)/cis in stage Ⅳ non-small cell lung cancer (NSCLC) patients (pts).J Clin Oncol,2007,25:7605.
  • 10Santarpia M,Garrido P,Gonzalez-Larriba J,et al.XPD 312 single nucleotide polymorphism (SNP) in stage Ⅲ A-B non-small cell lung cancer (NSCLC) patients (p) <59 years (y) treated with chemotherapy followed by surgery.J Clin Oncol,2007,25:7652.

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