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线虫线粒体基因组全序列分析研究进展 被引量:7

Research Progress on Analyses of Complete Mitochondrial Genomes for Nematodes
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摘要 线虫(nematode)种类繁多,生活方式多样,一部分线虫可寄生于动物和植物体内,引起线虫病(nematodiasis),其中旋毛虫病、猪蛔虫病等是重要的人兽共患寄生虫病,在中国和世界各地普遍流行,危害严重。本文将对线虫线粒体基因组的研究进展、应用和今后发展方向做一简要综述。迄今,已完成46种线虫的线粒体基因组全序列测定和分析。线虫线粒体基因组的碱基组成、基因结构、基因变异等方面有其特点,这些分析结果为线形动物门线粒体功能基因组学研究、比较基因组学研究、分子分类学研究、虫种(株)鉴定与分类、分子系统发育和进化分析等提供了重要依据和指导作用,为线虫病诊断、分子流行病学调查等分子检测方法的建立提供参考依据。 Nematodes(roundworms) are abundant with a variety of lifestyles,and many of them such as Trichinella spiralis,Ascaris suum and Brugia malayi are parasitic and of veterinary and medical importance causing substantial socioeconomic losses across China and worldwide.The review focuses on current progress,applifications and perspectives related to mitochondrial(mt) genomes(mtDNAs) and genomics of nematodes.Until now,complete mt genomes for 46 species of nematodes have been sequenced and analyzed.The mt gene content,arrangement,composition,variation and so on of nematodes are unique and provide important data concerning functional and comparative mitochondrial genomics,molecular taxonomy,specific species characterization,population genetics and systematics,and evolutionary history.Moreover,they lay the foundation for mtDNA-based methods for diagnosis and epidemiology of nematodiasis.
出处 《中国农业科学》 CAS CSCD 北大核心 2011年第6期1255-1265,共11页 Scientia Agricultura Sinica
基金 国家科技支撑计划项目(NO.2007BAD40B04) 公益性行业(农业)科研专项(200903036-07) 家畜疫病病原生物学国家重点实验室自主课题(SKLVEB2008ZZKT014)
关键词 线虫 线粒体基因组 基因结构 分类 nematode mitochondrial genome gene structure taxonomy
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  • 1Crimi M, Rigolio R. The mitochondrial genome, a growing interest inside an organelle. International Journal of Nanomedicine, 2008, 3(1): 51-57.
  • 2Hu M, Chilton N B, Gasser R B. The mitochondrial genomics of parasitic nematodes of socio-economic importance: recent progress, and implications for population genetics and systematics. Advances in Parasitology, 2004, 56:133-212.
  • 3Hu M, Gasser R B. Mitochondrial genomes of parasitic nematodes-progress and perspectives. Trends in Parasitology, 2006, 22(2): 78-84.
  • 4Lupi R, de Meo P D, Picardi E, D'Antonio M, Paotetti D, Castrignan6 T, Pesole G, Gissi C. MitoZoa:A curated mitochondrial genome database of metazoans for comparative genomics studies Mitochondrion, 2010, 10(2): 192-199.
  • 5Le T H, Blair D, McManus D P. Mitochondrial genomes of parasitic flatworms. Trends in Parasitology, 2002, 18:206-213.
  • 6Pigaoeau G, Eyre-Walker A. Evidence for variation in the effective population size of animal mitochondrial DNA. PLoS ONE, 2009, 4(2): e4396.
  • 7Whitehead A. Comparative mitochondrial genomics within and among species ofkillifish. BMCEvolution Biology, 2009, 9(1): 11.
  • 8Mueller R L, Boore J L. Molecular mechanisms for extensive mitochondrial gene rearrangement in plethodontid salamanders. Molecular Biology and Evolution, 2005, 22(10): 2104-2112.
  • 9Dowton M, Cameron S L, Dowavic J 1, Austin A D, Whiting M F. Characterization of 67 mitochondrial tRNA gene rearrangements in the Hymenoptera suggests that mitochondrial tRNA gene position is selectively neutral. Molecular Biology and Evolution, 2009, 26(7): 1607-1617.
  • 10Okimoto R, Macfarlane J L, Wolstenholme D R. Evidence for the frequent use of TTG as the translation initiation codon mitochondrial protein genes in the nematodes, Ascaris suum Caenorhabditis elegans. Nucleic" Acids Research, I990, I8 6113-6118 and (20):.

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