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体外受精助孕后并发异位妊娠相关因素分析 被引量:17

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摘要 目的:探讨体外受精-胚胎移植助孕中异位妊娠的发生率与影响因素。方法:回顾性分析2005年4月至2009年5月在我院接受常规体外受精(IVF)、卵胞浆内单精子显微注射(ICSI)、冻融胚胎移植(FET)助孕的临床资料,分析不同助孕方式中异位妊娠的发生率,并以同期新鲜IVF(ICSI)周期获宫内妊娠者作为对照组,分析不孕原因及胚胎移植距宫底的深度与异位妊娠的关系。结果:接受助孕治疗1305周期,临床妊娠540例(41.38%),发生异位妊娠33例,发生率为4.14%。其中宫内外同时妊娠7例,发生率为1.296%。3种助孕方式(IVF-ET、ICSI和FET)比较,FET妊娠率明显低于新鲜周期(P<0.05)。3组间异位妊娠发生率比较,ICSI组显著低于FET组(P<0.05),ICSI组也明显低于IVF组,但差异无统计学意义(P>0.05)。29例发生异位妊娠患者助孕指征为输卵管因素,占87.88%,显著高于对照组(P<0.05)。移植胚胎的深度距宫底≤1.0cm时异位妊娠发生率显著高于>1.0cm者(P<0.05)。结论体外受精助孕后异位妊娠发生率较自然受孕人群高,输卵管因素是IVF-ET中发生异位妊娠的高危因素,移植胚胎距离宫底1.1~2.0cm可有效减少异位妊娠的发生。
出处 《实用医学杂志》 CAS 北大核心 2011年第6期1019-1021,共3页 The Journal of Practical Medicine
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参考文献14

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二级参考文献19

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