摘要
目的:了解机关人员胆囊结石发生率,探讨胆囊结石产生的相关因素。方法:受检者空腹测血总胆固醇、甘油三脂、高密度脂蛋白及血糖。胆囊结石的诊断皆以B超影像诊断为依据。1912例按性别、年龄、有无胆囊结石和有无糖尿病分组,对比分析这些因素及血脂与胆囊结石发生率之间的关系。结果:总体结石发生率为8.79%,随年龄增长发生率增高。女性(11.2%)明显高于男性(7.10%),P<0.01。胆囊结石者TC、TG高于无结石者,在女性中有统计学差异,P<0.01和P<0.05。男女50岁以上者TC、TG高于49岁以下者,女性中TC(P<0.01),女性中TG和男性中TC,P<0.05。糖尿病者结石发生率23.5%,明显高于无糖尿病者的8.52%,P<0.01,但与男女高龄组(70~79)岁比较差异无显著性。结论:①年龄增长及女性是胆囊结石的主要危险因素。②高血脂(TC、TG)与胆囊结石呈正相关。③糖尿病增加胆囊结石的危险,如有较大样本,便作性别、年龄配对的对比分析,将更具说服力。
Objective:To understand the incidence of gallbladder stones in officers and to explore the associated factorsín developing gallbladder stones.Methods:Venous blood samples after an over night fast were obtained for measurements of serum lipids and plasma glucose.The diagnosis of gallbladdder stones was made by ultrasonography.1912 subjects received examinations were grouped according to sex、age、with or without gallbladder stones and dabetes to compare the relationship of the factors and serum lipids to incidence of gallbladder stones.Results:The overall incidence was 8.79%.It increased with age,and it became higher in women(11.20%)than in men(7.10%),P<0.01.The level of TC.TGwas higher in subjects with gallbladder stones than the ones without it,which had statistical difference in women,P<0.01 and P<0.05.It was also higherín subjects of 50 and above than in 49 and below,TC in women P<0.01;TC in men and TGin women,P<0.05.235%of subjects with diabetes were found gallbladder stonens and significantly higher than in subjects without diabetes(8.52%),P<0.01.But no difference was shown when compared with men and women advanced in years.Conclusion;①Increasing age and women are two major risk factors in developing gallbladder stones②Higher serum lipids(TC、TG)are positively correlation with gallbladder stones③Diabetes increases the risk of gallbladder stones,which would be more convincing if a large sample is given aud the pairs are matched for sex.age.
作者
付国庆
杨新城
陆瑛
赵颍
Fu Guoqing;Yang Xincheng;Lu Ying(Coal General Hospitai,Beijng,100028)
出处
《河北医学》
CAS
1999年第9期15-18,共4页
Hebei Medicine
关键词
胆囊结石
胆固醇
甘油三脂
糖尿病
病因
Gallbladder stones
totalcholesterol[TC]
triglycerides[TG]
diabetes
