摘要
目的:观察高血压病患者血压晨峰(morning blood pressure surge,MBPS)与心脏肥大和颈动脉内膜-中膜厚度(IMT)的关系。方法:高血压病患者386例。根据动态血压检测结果,分为晨峰组(146例)和非晨峰组(240例),全部病例同步记录24 h动态血压和动态心电图,观察指标为24 h动态血压参数;超声技术检测左室质量指数(LVMI)、左房内径(LAD)、颈动脉IMT等指标。结果:晨峰组与非晨峰组比较:LVMI分别为(119±21)g/m2和(92±12)g/m2(P<0.01);LAD分别为(46±11)mm与(38±10)mm(P<0.05);颈动脉IMT分别为(1.36±0.24)mm与(0.92±0.18)mm(P<0.01);左室肥厚(LVH)的检出率分别为67%与30%(P<0.01)。结论:与无血压晨峰的高血压病患者比,具有血压晨峰的高血压病患者LVH和颈动脉硬化更显著,心血管重构更显著,左心房内径更大。
AIM： To evaluate the association between morning blood pressure surge（MBPS） and cardiovascular remodeling in hypertensive patients.METHODS： A cohort of 386 patients with hypertension under 24 h ambulatory blood pressure monitoring were categorized as MBPS group（n=146） and non-MBPS group（n=240）.Left ventricular mass index（LVMI） and thickness（IMT） of carotid artery were measured by ultrasonography in all patients and left ventricular hypertrophy（LVH）,left atrial dimension（LAD） and intima-media thickness were compared between groups.RESULTS： Compared with those in the non-MBPS group,LVMI [（119±21） g/m2 vs.（92±12） g/m2,P〈0.01],LAD [（46±11） mm vs.（38±10） mm,P〈0.05],IMT of carotid artery [（1.36±0.24） mm vs.（0.92±0.18） mm,P〈0.05] and LVH（67% vs.30%,P〈0.01） were significantly higher in the MBPS group.CONCLUSION： Hypertensive patients with MBPS have more severe LVH and carotid atherosclerosis and larger LAD compared with those of hypertensive patients without MBPS.MBPS is associated with more significant cardiovascular remodeling.
出处
《心脏杂志》
CAS
2011年第1期80-81,85,共3页
Chinese Heart Journal
关键词
血压
晨峰
心血管重构
左心室肥厚
颈动脉
morning blood pressure surge； cardiovascular remodeling； left ventricular hypertrophy； carotid artery；
