摘要
目的 调查重症急性胰腺炎（SAP）患者器官功能衰竭的患病率,分析其发病的危险因素.方法 回顾性分析2000年3月至2009年10月于山西省晋中市第一人民医院ICU住院的186例SAP患者.SAP诊断依据2006年中华医学会外科学会制订的重症急性胰腺炎诊断标准.收集年龄、性别、病因、并存病、APACHE Ⅱ评分、CECT胰腺坏死程度、CT严重性指数（CTSI）、腹腔间隔窒综合征（ACS）、器官功能衰竭数目与死亡人数等资料.计算器官功能衰竭的患病率和病死率.采用非条件多因素Logistic回归分析方法确定器官功能衰竭的危险因素.结果 186例SAP患者中,96例患器官功能衰竭.96例SAP器官功能衰竭患者中,47例死亡.SAP患者器官功能衰竭患病率与年龄、并存病数目、APACHEⅡ评分、CECT胰腺坏死程度、CTSI和ACS显著相关.器官功能衰竭数目随着年龄、并存病数目、APACHEⅡ评分,CECT胰腺坏死程度增加显著增加.进入非条件多因素Logistic回归方程的因素有年龄、并存病数目、APACHEⅡ评分、CECT胰腺坏死程度、CTSI和ACS.结论 SAP患者器官功能衰竭的患病率为51.6%,与之相关的病死率为49.0%,年龄、并存病数目、APACHEⅡ评分、CECT胰腺坏死程度、CTSI和ACS是SAP患者器官功能衰竭的独立危险因素.
Objective To determine the prevalence of organ failure and its risk factors in patients with severe acute pancreatitis（SAP）. Method A retrospective analysis was conducted in 186 patients, who were hospitalized in the intensive care unit of Jinzhong First People＇s Hospital with SAP between March 2000and October 2009. SAP patients met the diagnostic criteria of SAP set by Surgery Society of Chinese Medical Association in 2006. The variables included age, gender, etiology of SAP, the number of comorbidit, APACHE Ⅱ score, CECT pancreatic necrosis, CT Severity Index （ CTSI ）, abdomen compartment syndrome （ACS） ,the number of organ failure and the number of death. The prevalence and mortality of organ failure were calculated. The above-mentioned variables were analyzed by unconditional multivariate logistic regression analysis to determine the independent risk factors for organ failure in SAP. Results Of 186 patients, 96had organ failure. In 96 patients with organ failure, 47 died. There was a significant association between the prevalence of organ failure and age, the number of comorbidit, APACHE Ⅱ score, CECT pancreatic necrosis, CTSI, ACS. An increase in age, the number of comorbidit, APACHE Ⅱ score, CECT pancreatic necrosis correlated with an increase in the number of organ failure. Age, the number of comorbidit, APACHE Ⅱ score,CECT pancreatic necrosis, CTSI and ACS went into the unconditional multivariate logistic regression equation. Conclusions Organ failure occurred in 51.6% of 186 patients with SAP. The mortality of SAP with organ failure is 49.0%. Age, the number of comorbidit, APACHE Ⅱ score, CECT pancreatic necrosis,CTSI and ACS are independent risk factors of organ failure.
出处
《中华急诊医学杂志》
CAS
CSCD
北大核心
2011年第2期156-159,共4页
Chinese Journal of Emergency Medicine
