摘要
目的对ICU高龄患者发生院内感染后的病原培养阳性结果进行统计分析并统计铜绿假单胞菌的耐药情况,为临床预防院内感染和治疗用药提供依据。方法对2008年1月～2010年10月我院ICU的超过70岁高龄患者病原培养阳性结果及首要病原药敏情况进行统计分析。结果 2008年1月～2010年10月共有78名患者的病原菌阳性标本378例,其中痰标本285例(75.40%),血标本42例(11.11%),中段尿27例(7.14%),导管14例(3.70%),其他标本为10例(2.65%)。培养结果包括非发酵菌199例(52.64%),真菌45例(11.90%),凝固酶阴性葡萄球菌35例(9.26%),金黄色葡萄球菌23例(6.08%)。治疗铜绿假单胞菌感染的敏感药物包括多粘菌素E,阿米卡星和庆大霉素。结论 ICU高龄患者院内感染的部位主要发生在下呼吸道,感染病原以非发酵菌、真菌、凝固酶阴性葡萄球菌为主。对于治疗铜绿假单胞菌感染,比较敏感的药物包括多粘菌素,阿米卡星和庆大霉素。
Objective To prevent the nosocomial infection and provide reliable reference in the use of antibiotics, the pathogen in aged patients of ICU and the sensitivity of pseudomonas aeruginosa were analyzed. Method The results of pathogen culture positive of the patients older than 70 years who were nosocomial infection in ICU from Jan 1, 2008 to Oct 31, 2010 were analyzed, as well as the primary source of the disease susceptibility. Result A total of 378 pathogens were isolated from 78 patients. The most popular isolates are from spu- tum （75.40 %） and blood （11.11%）. Nonfermenter was the main pathogen （199 strains, 52.64 %）. There were 45 isolates of fungal strains （11.90 %）. Coagulase-negative staphylococcus 35 strains （9.26 %） are more common than Staphylococcus aureus （6.08 %）. Pseudomonas aeruginosa was the dominant composition of the nosocomial infection, and the sensitive antibiotics included polymyxin E,amikacin and gentamicin. Conclusion Location of ICU nosocomial infection in elderly patients was the lower respiratory tract, nonfermenter, fungi and coagulase-negative staphylococcus are dominant pathogens. Polymyxin E, arnikacin and gentamicin are sensitive antibiotics to cure pseudomonas aeruginosa infection.
出处
《临床医学工程》
2011年第3期455-456,共2页
Clinical Medicine & Engineering
基金
2010年度深圳市科技计划项目"选择性消化道去污染防治重症监护病房医院感染的系统评价"(编号:201003262)
关键词
ICU
高龄患者
病原菌
院内感染
ICU
Elderly patients
Pathogen
Nosocomial infection
