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急性心肌梗死溶栓治疗对住院病死率的影响

Observation of effects of thrombolytic therapy on in-hospital mortality in patients with acute myocardial infarction
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摘要 目的 评价溶栓治疗对急性心肌梗死(AMI)的近期疗效。方法 对自1989年9月~1998年4月收治的AMI患者906例分别以溶栓冠脉再通、未再通与未溶栓三组的住院病死率及其影响因素作比较。结果 溶栓再通组死亡率明显低于未再通组(5.2%,15.5%,P<0.01)。AMI合并室颤、室速、急性肺水肿、心源性休克的病人,再通组的住院病死率明显低于未再通组(P<0.01)。而溶栓组死亡率与溶栓未再通组死亡率无显著性差别(P>0.05)。结论 溶栓再通对降低住院病死率具有独立的良好作用。 Objective To study the effects of thrombolytic therapy on acute prognosis in patients with acute myocardial infarction. Methods 906 cases since September 1989 to April 1998 in our hospital, including 192 cases experienced reper-fusion,161 cases non-reperfusion and 549 cases non experienced thrombolysis.the in-hospital mortality and its effective factors were compared. Results That cases in-hospital mortality of the reperfusion group (5. 2%) was significantly lower than that of non-reperfusion group(15. 5%)(P<0. 01). Moreover,the different of mortality in patients complicated with ventricular fibrillation, ventricular tachycardia,acute pulmonary edema and cardiogenic shock between reperfusion group and non-reperfusion group were still significant (P < 0. 01). While the in-hospital mortality of non-thrombolytic group and non-reperfusion group were 12. 2% and 15. 5% respectively (P>0. 05). Conclusion Reperfu-sion has an independent effect on decreasing the in-hospital mortality of patients.
出处 《实用心脑肺血管病杂志》 1999年第3期155-157,共3页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词 急性 心肌梗死 溶栓治疗 住院病死率 Acute myocardial infarction Thrombolytic therapy In-hospital mortality
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参考文献4

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  • 2The collaborative study group for national multicenter clinical trial of urokinase thrombolytic therapy (Correspondence: Hu Dayi, Xu Zhimin. Beijing Red Cross Chao Yao Hospital, Beijing 100020).尿激酶治疗急性心肌梗塞多中心临床试验1406例总结[J].中华心血管病杂志,1997,25(3):176-179. 被引量:138
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二级参考文献1

  • 1团体著者,中华心血管病杂志,1991年,19卷,137页

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