摘要
目的探讨重型肝炎患者肝移植围手术期的处理方法。方法 回顾性分析2003年1月至2009年10月间接受原位肝移植的42例重型肝炎患者的临床资料。结果 42例重型肝炎患者中术后存活36例(86%)。术后并发腹腔出血6例,胆道并发症4例,无血管并发症。术后均出现不同程度的肾功能障碍;术后出现精神症状者28例,出现癫者3例;出现肺部感染者22例,出现排斥反应3例。结论 术前正确评估患者病情,术后及时、有效地处理各种并发症是提高重型肝炎患者肝移植成功率的关键。
Objective To investigate the perioperative management of patients with severe hepatitis undergoing orthotopic liver transplantation.Methods The clinical data of 42 patients with severe hepatitis were retrospectively analyzed,who underwent orthotopic liver transplantation from January 2003 to October 2009.Results In 42 patients,36 patients survived after operation.The total survival rate was 86 %（36/42）.After transplantation,intraperitoneal hemorrhage occurred in 6 cases,biliary complications occurred in 4 patients and no vascular complication occurred.All patients developed renal dysfunction in varying degrees.Psychiatric symptom occurred in 28 cases.Epilepsy occurred in 3 patients.Pulmonary infection occurred in 22 patients and rejection occurred in 3 patients.Conclusion Reasonable preoperative evaluation of patients＇ condition and effectual treatment of various kinds of complications in time are the key point to improve the success rate of severe hepatitis which are treated by orthotopic liver transplantation.
出处
《器官移植》
CAS
2011年第2期68-72,共5页
Organ Transplantation
关键词
重型肝炎
肝移植
并发症
围手术期
Severe hepatitis
Liver transplantation
Complication
Perioperative period
