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HPLC法测定紫杉醇注射液中紫杉醇的含量 被引量：2

Determination of the paclitaxel contents in Paclitaxel Injection by HPLC
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摘要 目的:对新乡市中心医院新购置的一批紫杉醇注射液进行含量测定。方法:采用HPLC法,色谱条件C18 Diamond(150 mm×4.6 mm)柱;检测波长227 nm;流速1.0 mL/min;柱温25℃;流动相冰醋酸-乙腈-水(0.1∶40∶10)。结果:紫杉醇注射液质量检验合格。结论:HPLC法测定紫杉醇含量快速准确。 Objective：To determine the paclitaxel contents in Paclitaxel Injection recently bought by Xinxiang Central Hospital.Methods：The Paclitaxel contents were determined by HPLC method with column： C18 Diamond（150 mm×4.6 mm）,detection wave： 227 nm,column temperature： 25 ℃,mobile phase： aqueous acetic acid-acetonitrile-water：（0.1∶40∶10）.Results：The quantity of Paclitaxel Injection detected was up to the standard.Conclusion：HPLC is the accurate and rapid method for the paclitaxel contents.
作者 孙利伟 赵辉 刘建青
机构地区 新乡市中心医院药剂科 河南大学药学院药物分析教研室 新乡市药品检验所
出处 《河南大学学报（医学版）》 CAS 2011年第1期42-44,共3页 Journal of Henan University:Medical Science
关键词 紫杉醇 高效液相色谱法 含量测定 Paclitaxel HPLC Content determination
分类号 R931 [医药卫生—生药学]
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参考文献6

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二级参考文献22

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共引文献38

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河南大学学报（医学版）
2011年 第1期

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