摘要
采用24h动态心电图检测58例2型糖尿病伴下肢神经病变组、59例2型糖尿病不伴下肢神经病变组（非下肢神经病变组）和50例对照组的心率变异性，比较其频域参数的水平及昼夜间的变化。结果显示非下肢神经病变组、下肢神经病变组较对照组频域指标减小，平均心率增加；昼夜间比较在对照组差异有统计学意义，在非下肢神经病变组昼夜节律发生改变，在下肢神经病变组昼夜节律消失。提示糖尿病不伴和伴下肢神经病变均存在自主神经功能受损，后者受损更明显。
[ Summary ] Heart rate variability （ HRV ） analysis and its circadian rhythm （ CR ） were determined in 58 patients with type 2 diabetes mellitus with lower extremity neuropathy （ diabetic neuropathy group）, 59 patients with type 2 diabetes mellitus without lower extremity neuropathy（ diabetes group）, and 50 healthy controls according to 24- hour Holter recording. Frequency domain parameters of HRV were significantly decreased in both diabetes groups. Frequency domain parameter of HRV in healthy controls, and daytime/nighttime difference were statistically significant. CR of HRV was changed in diabetes group and disappeared in diabetic neuropathy group. Impaired and seriously impaired autonomic nervous function developed in type 2 diabetes mellitus without and with lower extremity neuropathy respectively.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2011年第2期142-144,共3页
Chinese Journal of Endocrinology and Metabolism
关键词
糖尿病
2型
糖尿病自主神经病变
心率变异性
昼夜节律
Diabetes mellitus, type 2
Diabetic autonomic neuropathy
Heart rate variability
Circadian rhythm
