期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

氧化应激与糖尿病大鼠nephrin表达及足细胞凋亡的关系 被引量：5

原文传递
导出
摘要 本研究观察，氧化应激对糖尿病大鼠nephrin表达改变及足细胞凋亡的影响，以探讨糖尿病大鼠蛋白尿发生发展的分子机制。
作者 曾庆菊 贾汝汉 王晋文 段玉敏
机构地区 延安医院肾内科 武汉大学人民医院肾内科
出处 《中华肾脏病杂志》 CAS CSCD 北大核心 2011年第2期132-134,共3页 Chinese Journal of Nephrology
关键词 NEPHRIN 糖尿病大鼠 细胞凋亡 氧化应激 分子机制 蛋白尿
分类号 R587.1 [医药卫生—内分泌]
  • 相关文献

参考文献5

  • 1Nava M,Romero F,Quiroz Y,et al.Melatonin attenuates aute renal failure and oxidative stress induced by mercuricchloride in rats.Am J Physiol,2000,279:F910-F918.
  • 2Benigni A,Gagliardini E,Remuzzi G.Changes in glomerular perm-selectivity induced by angiotensin Ⅱ imply podocyte dysfunction and slit diaphragm protein rearrangement.Semin Nephrol,2004,24:131-140.
  • 3邢燕,丁洁,范青锋,管娜.足细胞分子高表达致阿霉素肾病大鼠发生蛋白尿[J].中华肾脏病杂志,2006,22(1):27-32. 被引量：39
  • 4Wharram BL,Goyal M,Wiggins JE,et al.Podocyte depletion causes glomerulosclerosis:Diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene.J Am Soc Nephrol,2005,16:2941-2952.
  • 5Huber TB,Hartleben B,Kim J,et al.Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling.Mol Cell Biol,2003,23:4917-4928.

二级参考文献19

  • 1范青锋,丁洁,张敬京,管娜,邓江红.podocin基因敲低对小鼠足细胞nephrin和α-actinin表达与分布的影响[J].中华肾脏病杂志,2004,20(5):325-329. 被引量：4
  • 2Kestila M,Lenkkeri U,Mannikko M,et al.Positionally cloned gene for a novel glomerular protein nephrin is mutated in congenital nephrotic syndrome.J Mol Cell,1998,1:575-582.
  • 3Boute N,Gribouval O,Roselli S,et al.NPHS2,encoding the glomerular protein podocin,is mutated in autosomal recessive steroid-resistant nephritic syndrome.Nat Genet,2000,24:349-354.
  • 4Shih NY,Li J,Karpitskii V,et al.Congenital nephrotic syndrome in mice lacking CD2-associated protein.Science,1999,286:312-315.
  • 5Kaplan JM,Kim SH,North KN,et al.Mutations in ACTN4,encoding α-actinin-4,cause familial focal segmental glomerulosclerosis.Nat Genet,2000,24:251-256.
  • 6Patrakka J,Ruotsalainen V,Ketola I,et al.Expression of nephrin in pediatric kidney diseases.J Am Soc Nephrol,2001,12:289-296.
  • 7Koop K,Eikmans M,Baelde HJ,et al.Expression of podocyte-associated molecules in acquired human kidney diseases.J Am Soc Nephrol,2003,14:2063-2071.
  • 8Luimula P,Sandstrom N,Novikov D,et al.Podocyteassociated molecules in puromycin aminonucleoside nephrosis of the rat.Lab Invest,2002,82:713-718.
  • 9Sanden SK,Wiggins JE,Goyal M,et al.Evaluation of a thick and thin section method for estimation of podocyte number,glomerular volume,and glomerular volume per podocyte in rat kidney with Wilms' tumor-1 protein used as a podocyte nuclear marker.J Am Soc Nephrol,2003,14:2484-2493.
  • 10Nakatsue T,Koike H,Han GD,et al.Nephrin and podocin dissociate at the onset of proteinuria in experimental membranous nephropathy.Kidney Int,2005,67:2239-2253.

共引文献38

同被引文献55

  • 1陈丽,刘晓城,宁勇.姜黄素对糖尿病大鼠肾脏病变的作用及对肾脏Smad7表达的影响[J].华中科技大学学报（医学版）,2004,33(4):438-440. 被引量：11
  • 2梁超,袁亮,吴永贵,董婧,任克军,张炜,方芳,郝丽,张伯科.FK506对糖尿病大鼠早期肾脏肥大的抑制作用及机制[J].中华肾脏病杂志,2007,23(4):230-234. 被引量：12
  • 3Meng B, Li J, Cao H. Antioxidant and antiinflammatory activities of curcumin on diabetes mellitus and its compli- cations [ J ]. Curr Pharm Des ,2013,19 ( 11 ) :2101-13.
  • 4Khan SR. Stress oxidative: nephrolithiasis and chronic kidney diseases [ J]. Minerva Med,2013,104( 1 ) :23-30.
  • 5Leung JC, Chan LY,Tang SC, et al. Oxidative damages in tubular epithelial cells in IgA nephropathy: role of crosstalk between angiotensin II and aldosterone [ J ]. J Transl Mcd ,2011,9 ( 169 ) : 1-15.
  • 6Stanton RC. Oxidative stress and diabetic kidney disease [ J ]. Curt Diab Rep ,2011,11 (4) :330-336.
  • 7Khan SR. Is oxidative stress, a link between nephrolithiasis and obesity ,hypertension, diabetes, chronic kidney disease, metabolic syndrome[ J~. Urol Res,2012,40(2) :95-112.
  • 8Shen GX. Oxdative stress and diabetic cardiovascular disorders: roles of mitochondria and NADPH oxidase [ J]. Can J Physiol Pharmaeo1,2010,88(3 ) :241-248.
  • 9Fleenor BS, Sindler AL, Marvi NK, et al. Curcumin amel- iorates arterial dysfunction and oxidative stress with ag- ing [J]. Exp Gerontol,2013,48(2) :269-276.
  • 10Gadallah MF,Lynn M,Work J. Case report : mannitol neph- mtoxicity syndrome: role of hemodialysis and postulate of mechanisms [J]. Am J Med Sci,1995,~9(4) :219-222.

引证文献5

二级引证文献55

中华肾脏病杂志
2011年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部