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脉压差与老年高血压病患者动脉硬化形成的关系研究 被引量:7

Study of correlation of pulse pressure and formation of artery atherosclerosis in old aged patient with hypertension
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摘要 目的老年高血压是动脉粥样硬化形成的因素之一。老年高血压具有脉压差大的特点。本文探讨脉压差与老年高血压患者动脉粥样硬化形成的关系。方法以98例老年高血压患者为对象,按24h平均脉压差大小分为<60mm Hg、60~69mm Hg和≥70mm Hg三组。用彩色多普勒超声检查颈动脉粥样硬化斑块及最大内膜中层厚度(IMT)。对比分析脉压差大小与颈动脉粥样硬化斑块发生率和IMT之间关系。结果本研究结果显示,随着脉压差的逐渐加大,老年高血压病人的颈动脉最大内膜中层厚度逐渐增加,颈动脉粥样硬化斑块发生率也跟着逐渐增高。结论脉压差增大可促进动脉粥样硬化斑块的形成和发展。脉压差是老年高血压病人动脉硬化的良好预测因子之一。 Objective Hypertension is a risk factor of atherosclerosis in old aged patient with hypertension.Old aged patients with hypertension have a feature of the high pulse pressure.The correlation of pulse pressure and the formation of artery atherosclerosis was studied in old aged patient with hypertension in this paper.Methods Totally 98 old aged patients with hypertension were selected.According to average pulse pressure measured in 24 hours,the patients were divided into three groups: 〈60mm Hg group,60-69mm Hg group and ≥70mm Hg group.Carotid atheroslerotic plague and carotid intimal-medial thickness(IMT) were measured by the Doppler Ultra Sound echocardiography.The correlation of the pulse pressure and rate of Carotid atheroslerotic plague and IMT were analyzed.Results The rate of carotid atheroslerotic plague and carotid intimal-medial thickness were gressively increased with the increasing of pulse pressure in old aged patient with hypertension.Conclusions The high pulse pressure may promote the forming and developing of atherosclerosis.Pulse pressure is a good predictor of atherosclerosis in old aged patient with hypertension.
出处 《医药论坛杂志》 2011年第1期36-37,共2页 Journal of Medical Forum
关键词 脉压差 高血压 动脉粥样硬化 颈动脉内膜中层厚度 Pulse pressure Hypertension Atherosclerosis Carotid intimal - medial thickness
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  • 5翟丽华,董少红,李光展,杨纯玉,温爱惠,陈王英.高血压病患者动态脉压与颈动脉粥样硬化关系的研究[J].中国动脉硬化杂志,2001,9(2):143-145. 被引量:24

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