摘要
目的分析江苏省无锡地区泌尿生殖系统支原体属的感染状况及其对抗菌药物的敏感性,为临床治疗支原体感染的抗菌药物选择提供参考依据。方法收集2008-2009年来无锡市人民医院就诊的5200例男女性生殖道感染者病灶部拭子样本(男:尿道拭子,女:阴道拭子),采用法国生物梅里埃公司IST2支原体试剂盒对患者标本进行支原体培养鉴定及药敏试验。结果 5200例男、女性生殖道感染者解脲脲支原体(Uu)阳性1783例,占34.3%,人支原体(Mh)阳性556例占10.7%;支原体属耐药率最低的抗菌药物是普那霉素,耐药率<2.0%,耐药性最高的抗菌药物是氧氟沙星和环丙沙星,耐药率>85.0%。结论支原体属感染中,Uu感染率最高,氧氟沙星、环丙沙星不能作为治疗支原体属感染的首选药物。
OBJECTIVE To investigate the infection status of mycoplasma in urogenital tract and the antibiotic susceptivity in Wuxi and provide reference for effective clinical therapy and control to mycoplasma infection.METHODS A total of 5200 swab specimen from urogenital tract infected patients who were treated in Wuxi people's hospital from 2008 to 2009 have been gathered(male: urethra swab,female:vagina swab).IST2 mycoplasma detection kits(Bio-Merieux,France) were used to detect the mycoplasma as well as their drug susceptibilities.RESULTS Totally 1783 patients were infected the Ureaplasma urealyticum(Uu),with a positive rate of 34.3% and 556 patients were infected the Mycoplasma hominis(Mh),with a positive rate of 10.7%.Drug sensitivity test demonstrated that mycoplasma was highly resistant to ofloxacin and ciprofloxacin(〉85.0%),but lowest resistant rate to pristinamycin(〈2.0%).CONCLUSIONS The infection rate of U.urealyticum infection is highest among the mycoplasma infection.Ofloxacin and ciprofloxacin can not be use as the primary drugs for therapy of mycoplasma infection.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第6期1272-1273,共2页
Chinese Journal of Nosocomiology
关键词
生殖道感染
支原体属
药敏率
Urogential tract infection
Mycoplasma
Drug sensitivity rate