摘要
目的:研究苦楝皮Melia azedarach L.的化学成分。方法:采用硅胶柱色谱技术分离纯化,通过光谱学方法鉴定化合物的结构。结果:分离并鉴定出7个化合物,分别为4,8-二羟基-1-四氢萘醌(isosclerone,Ⅰ),梣酮(fraxinellone,Ⅱ),苦楝皮萜酮(kulinone,Ⅲ),苦楝萜酮内酯(kulactone,Ⅳ),南岭楝酮B(dubione B,Ⅴ),苦楝酸(kulonic acid,Ⅵ)和β-谷甾醇(β-sitosterol,Ⅶ),丁二酸(succinic,Ⅷ),5-(羟甲基)-2-呋喃甲醛[5-(hydroxymethyl)-2-furaldehyde,Ⅸ]。结论:化合物Ⅰ,Ⅷ和Ⅸ系首次从该植物中分得。
Objective：To study the chemical constituents of Melia azedarach.Method：The chemical constituents were isolated and purified by column chromatography,and their structures were identified by spectroscopic analysis.Result：Seven compounds were isolated and identified as isosclerone（Ⅰ）,fraxinellone（Ⅱ）,kulinone（Ⅲ）,kulactone（Ⅳ）,dubione B（Ⅴ）,kulonic acid（Ⅵ）,β-sitosterol（Ⅶ）,succinic acid（Ⅷ） and 5-（hydroxymethyl）-2-furaldehyde（Ⅸ）.Conclusion：CompoundsⅠ,Ⅷ and Ⅸ were isolated from this plant for the first time.
出处
《中国实验方剂学杂志》
CAS
北大核心
2011年第6期93-96,共4页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
苦楝皮
化学成分
结构鉴定
Melia azedarach； chemical constituents； structural identification；
