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老年高血压合并2型DM与胰岛功能的相关性研究

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摘要 [目的]探讨老年高血压合并2型糖尿病(DM)与胰岛功能的相关性.[方法]选择老年高血压合并2型DM患者54例(A组),无DM的高血压37例(B组),无原发高血压的DM患者33例(C组),检测并比较三组血清甘油三酯(TG)、空腹血糖(FBG)、餐后2小时血糖(PBG)、糖化血红蛋白(GHbA lc)、空腹胰岛素(FINS) 计算并比较胰岛素抵抗指数(HOMA-IR) 和胰岛B细胞功能指数(HOMA-IS).[结果]A组血清TG显著高于B和C组(P〈0.05) B组FBG、PBG 和GHbAlc显著低于A和C组(P〈0.05) 三组HOMA-IR两两比较均存在显著性差异(P〈0.05) B组HOMA-IS显著高于A组和C组(P〈0.05) A组GMP-140显著高于B、C组(P〈0.05).[结论]胰岛素抵抗在高血压合并2型DM患者中更为显著,高血压合并2型DM老年患者血清GMP-140水平明显升高.
出处 《医学临床研究》 CAS 2011年第2期308-309,共2页 Journal of Clinical Research
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