摘要
目的探讨脑白质改变(white matter changes,WMC)在老年男性人群中的发生率及脑区分布特.点。方法采用年龄相关性白质改变视觉评定表,对259例老年男性体检者左右半球的脑室旁、额区、颞区、顶枕区、幕下结构和基底节区脑白质改变进行评定,进一步分析WMC与年龄和脑区分布的关系。结果 WMC的发生率为89.6%,52.1%WMC达到中度以上。WMC的发生率随着年龄的增长而增加。额区是WMC的好发部位,依次为顶枕区、颞区、基底节和幕下。年龄相关性白质改变总分及各脑区评分均随年龄增长而有增高趋势,差异有统计学意义(P<0.05,P<0.01)。结论老年男性人群中普遍存在WMC,且随着年龄的增长,发生率增加,程度加重。额叶是WMC的好发部位。应警惕WMC对老年人的潜在危害。
Objectives To investigate the distribution of white matter changes（WMC） in normal elderly male population. Method 259 elderly male patients who received normal physical examination in this hospital were randomly selected. The WMC of various brain regions（peri-ventricular, frontal region, temporal region, parieto-occipital region, basal ganglia, infratentorial area） were assessed with Age-related WMC（ARWMC） scale, and the relations of WMC with age and the brain regions were analyzed. Results The incidence of WMC was 89.6 %, and more than half of the participants reached a moderate level according to ARWMC scale（52.1% and above）. The incidence of WMC at each brain region increased with age. WMC was most common in frontal region, followed by parieto-oceipital region, temporal region, basal ganglia, and infratentorial area. The trend that the total score and the mean score of ARWMC scale increased with age was significant （P 〈0.05,P 〈 0.01）. Conclusion WMC was common in elderly male population, and its incidence and the degree increased with age. WMC was more common in frontal region than in others. We should maintain vigilance for the potential danger of WMC in the elderly.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2011年第3期242-244,共3页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
基金
北京市自然科学基金(7082087)
关键词
脑白质疏松症
认知障碍
脑梗死
记忆障碍
磁共振成像
年龄因素
leukoaraiosis
cognition disorders
brain infarction
memory disorders
magnetic resonance imaging
age factors
