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自噬相关蛋白对固有免疫调控的研究进展 被引量：1

The researches on innate immunity regulated by autophagy-related proteins
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摘要 模式识别受体（PPRs）识别病原微生物成分，诱导机体产生固有免疫应答。固有免疫应答异常，可导致超强的炎症反应，并可引起自身免疫性疾病。因此，必须对固有免疫应答进行严格的调控，才能维持机体生理平衡稳定。近年来，研究发现细胞自噬（autophagy）对固有免疫应答有着重要的调控作用。 Pattern recognition receptors detect the components of microorganism and induce innate immunity. Aberrant activation of immune responses can cause super-reactive inflammation and lead to autoimmune diseases. Therefore, innate immunity must be strictly regulated to maintain physiological homeostasis. Recent studies have shown that cellular autophagy is vital for the regulation of innate immunity. We reviewed the progress in this area.
作者 傅占江
机构地区 中国人民解放军白求恩军医学院医学检验教研室
出处 《国际免疫学杂志》 CAS 北大核心 2011年第2期119-122,共4页 International Journal of Immunology
关键词 自噬 固有免疫 信号调控 Autophagy Innate immunity Signaling regulation
分类号 R3 [医药卫生—基础医学]
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参考文献28

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二级参考文献16

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共引文献5

同被引文献2

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二级引证文献2

国际免疫学杂志
2011年 第2期

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