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影响他克莫司疗效的相关因素分析 被引量:8

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摘要 目的:探讨影响他克莫司疗效的相关因素,为合理用药提供参考。方法:对国内、外的文献进行了系统性分析。结果:基因的多态性、病理生理状态、药动学、药效学之间的相互作用是影响他克莫司的疗效或产生不良反应的重要因素。结论:临床上使用他克莫司时,应关注个体的病理生理状态、遗传差异和药物的相互作用,以确保他克莫司的合理应用。
出处 《中国医院药学杂志》 CAS CSCD 北大核心 2011年第5期405-407,共3页 Chinese Journal of Hospital Pharmacy
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参考文献2

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二级参考文献22

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共引文献14

同被引文献81

  • 1余松峰,吴丽花,金晶,严盛,谢海洋,高金亭,郑树森.供体CYP3A5基因多态性影响肝移植术后FK506的个体化用药[J].中国药学杂志,2007,42(4):314-317. 被引量:8
  • 2徐芳,翟所迪,胡永芳.他克莫司发生药物相互作用的分子机制[J].中国药学杂志,2007,42(13):965-968. 被引量:17
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