摘要
目的 本文分析了大骨节病临床症状的检出率及分布规律,探讨和评价诊断本病意义和关节损害的特点。方法 选择大骨节病横断面流行病学调查中2913例非病区与病区健康、大骨节病病例的34个临床症状体征进行病例对照分析。结果①掌指骨X线异常病变是早期患者的主要表现,并仍存在于大骨节病不同程度的病例中;②下蹲障碍和指粗是大骨节病Ⅰ度、Ⅱ度、Ⅲ度病例与早期患者的显著不同体征;③关节损害的特点是从四肢到脊柱,并呈上、下肢对称性损害。结论 大骨节病临床症状体征的检出率与病情的严重程度有关,对进一步评价临床诊断指标有一定的重要意义。
The distributive characteristics of clinical symptoms and signs in Kashin - Beck disease (KBD) and non - KBD were investigated in this paper in order to understand the feature of damaged joints in KBD and to evaluate the diagnostic significance for this disease. Methods: 37 clinical symptoms and signs of 2 913 cases from KBD areas and non - KBD areas were analyzed in the cross section epidemiological survey of KBD. Results: ① The abnormal pathologic changes of metacarpal -phalanges on X - ray film of hands were main manifestations, and still appeared in the different degree cases with KBD. ② The limited squatting enlargement of finger joints in KBD patients from the first degree to the third degree significantly different from the early stage of this disease.③The characteristics of joint damage were developed from limbs to spine with symmetric changes between the upper lirnbs and the low limbs. Conclusion: The abnormal rate, of clinical symptoms and signs in KBD were related to the serious degree of the disease. It is important to evaluate the clinical diagnostic indexes for KBD.
出处
《中国地方病防治》
1999年第5期266-268,共3页
Chinese Journal of Control of Endemic Diseases
关键词
大骨节病
频率分布
诊断
临床症状
Kashia-Beck disease
Frequency distribution
Diagnosis
