摘要
目的:探讨靶控输注(TCI)咪唑安定复合氯胺酮用于小儿麻醉的可行性和安全性。方法:回顾性分析我院2010年6～7月外科收治住院的择期手术患儿30例临床资料。结果:①麻醉后低氧血症(SpO2<95%)的发生率在K组、MK组分别是6.67%、13.33%,无SpO2低于90%的病例;②TCI咪唑安定(200 ng/ml)复合氯胺酮时,K组和MK组氯胺酮的用量分别为(15.58±4.12)mg/kg和(8.65±1.54)mg/kg,减少44.49%;K组和MK组术后躁动,恶心呕吐发生率分别为20.00%和6.67%(P<0.05)。结论:TCI咪唑安定200 ng/ml用于儿童静脉麻醉是安全可行的,循环呼吸系统不良反应发生率低。
Objective：To investigate the feasibility and safety for pediatric anesthesia of TCI Midazolam combined with Ketamine.Methods：The clinical datas of 30 cases elective surgery in children in our hospital from June 2010 to July were retrospectively analyzed.Results：①The incidence of Anesthesia hypoxemia（SpO295%） in K group and MK group was 6.67%,13.33% respectively,non SpO2 less than 90% of cases;②TCI Midazolam（200 ng/ml） compound Ketamine,the dosage of Ketamine K group and MK group was（15.58±4.12） mg/kg and（8.65±1.54） mg/kg respectively,decreased 44.49%;the incidence of postoperative dysphoria,nausea and vomiting of K group and MK group was 20.00% and 6.67%（P0.05）.Conclusion：TCI Midazolam 200 ng/ml intravenous anesthesia for children is safe and feasible,incidences of adverse reaction of circulatory and respiratory system are low.
出处
《中国医药导报》
CAS
2011年第6期31-33,共3页
China Medical Herald
关键词
靶控输注
咪唑安定
氯胺酮
儿童
麻醉
Target controlled infusion
Midazolam
Ketamine
Children
Anesthesia
