摘要
目的观察阿德福韦酯联合杞菊地黄丸治疗肝肾阴虚型慢性乙型肝炎的疗效。方法 110例患者随机分为对照组和治疗组各55例,对照组给予阿德福韦酯10mg/d口服,治疗组在对照组的基础上加服杞菊地黄丸。两组均治疗6个月。检测比较HBV标志物及HBV-DNA、ALT等指标的变化。结果治疗组血清HBeAg阴转率、HBeAg/抗HBe血清转换率明显高于对照组(P<0.05),6个月后其HBV-DNA和ALT下降程度与对照组相比有显著差异(P<0.05)。结论阿德福韦酯联合杞菊地黄丸可明显提高肝肾阴虚型慢性乙肝患者的血清HBeAg阴转率、HBeAg/抗HBe血清转换率,并能明显降低HBV-DNA和ALT,是一种对肝肾阴虚型慢性乙肝较好的治疗方法。
Objective To observe the clinic effect of adefovir dipivoxil （ADV）combined with qiju dihuang pill on chronic hepatitis B （CHB）typed yin deficit of liver and kidney. Methods 110 CHB patients typed yin deficit of liver and kidney were divided into treatment group and control group randomly. The former were treated by adefovir dipivoxil combined with qiju dihuang pill,and the latter were treated by adefovir dipivoxil only. The two groups＇ overall treatment period were 6 months. Test the patients＇ HBeAg,HBeAg/an- ti-HBe, HBV-DNA,ALT,etc. Results After treatment,the treatment＇s HBeAg transfering into negative rate, HBeAg/anti-HBe transfering rate are higher than the control group （P〈0.05）,and the treatment group＇s HBV-DNA and ALT declining degree are larger than the control group （P〈0.05）. Conclusion Adefovir dipivoxil combined with qiju dihuang pill can obviously raise the HBeAg transferring into negative rate,HBeAg/anti-HBe transferring rate and reduce the HBV-DNA and ALT level,and is an effective treatment for the CHB typed yin deficit of liver and kidney.
出处
《中国现代医生》
2011年第3期38-39,共2页
China Modern Doctor
关键词
慢性乙型肝炎
肝肾阴虚型
阿德福韦酯
杞菊地黄丸
Chronic Hepatitis B
Yin Deficit of Liver and Kidney
Adefovir Dipivoxil
Qiju Dihuang Pill
