摘要
目的:通过报告1例sezary综合征以及文献复习提高对此病的认识。方法:报告1例sezary综合征,并对国内文献进行总结分析。结果:共26例sezary综合征患者,男性23例占88.5%,中位年龄59.5岁,主要表现为全身红皮病,伴有瘙痒,可出现淋巴结肿大、肝脾肿大。实验室检查发现白细胞升高,外周血中可找到sez-ary细胞。皮肤或淋巴结活检可发现sezary细胞。部分患者经以激素为主的治疗后获得缓解。结论:sezary综合征是一罕见的淋巴瘤,对此病的认识还需提高,国内尚需加强对细胞免疫分型和分子生物学的检测。
Objective：To improve the recognition of sezary syndrome.Method：A patient with sezary syndrome was reported and related literature were reviewed.Result：Twenty-six Patients including our patient were summarized,among which 23 patients were male （88.5%） and the median age was 59.5 years old. Sezary syndrome was characterized by generalized erythroderma,lymphadenopathy and enlargement of liver or spleen,and presence of Sezary cells in peripheral blood. Sezary cells could also be found in skin or lymph nodes. Glucocorticoid may be effective in partial patients.Conclusion：Sezary syndrome was rare. We should improve our recognition. Immuophenotype and molecular biology tests should be emphasized in our country.
出处
《临床血液学杂志》
CAS
2011年第1期22-24,共3页
Journal of Clinical Hematology
