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咖啡酸治疗奥美拉唑所致白细胞减少症疗效观察 被引量:11

Efficacy of caffeic acid tablets in treatment of leukopenia caused by omeprazole
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摘要 目的探讨咖啡酸片对奥美拉唑引起白细胞减少症的疗效。方法将奥美拉唑治疗后引起白细胞减少症的56例患者随机分为治疗组30例和对照组26例,治疗组给予口服咖啡酸片0.2 g,3次/d,疗程4周;对照组口服维生素B420 mg、鲨肝醇100 mg,3次/d,疗程4周。两组在治疗中每周复查1次血常规,观察治疗后白细胞上升的情况。结果治疗组升白细胞有效率93.3%,对照组53.8%,两组比较差异有统计学意义(P<0.05)。结论咖啡酸片对奥美拉唑引起白细胞减少症有很好的疗效,有临床应用价值。 Objective To analyze the efficacy of caffeic acid tablets in treatment of leukopenia caused by omeprazole.Methods Fifty-six patients with leukopenia caused by omeprazole were randomly divided into treatment group of 30 patient sand control group of 26 patients.The treatment group was given oral caffeic acid tablets 0.2 g,tid,for 4 weeks;the control group took Vitamin B4 20 mg and batilol 100 mg,tid,for 4 weeks.Blood was examined every week during treatment for both groups to observe rise of white blood cells.Results The effective rate was 93.3% in the treatment group and 53.8% in the control group,with significant difference between the two groups(P〈0.05).Conclusion The caffeic acid tablet has efficacy in treatment of leukopenia caused by omeprazole and it has value of clinical application.
出处 《临床医学》 CAS 2011年第1期10-11,共2页 Clinical Medicine
关键词 咖啡酸片 奥美拉唑 白细胞减少症 疗效 Caffeic acid tablets Omeprazole Leukopenia Efficacy
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  • 1胡领,姚金成.奥美拉唑的不良反应[J].中南药学,2003,1(4):251-253. 被引量:9
  • 2国家药典委员会.中华人民共和国药典化学药物和生物制药卷临床用药须知[Z].北京:人民卫生出版社,2005:277-779.

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