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连续性肾脏替代治疗对顽固性心力衰竭的疗效观察 被引量:5

Efficacy of continuous renal replacement therapy in patients with intractable heart failure
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摘要 目的探讨连续性肾脏替代治疗(CRRT)在救治顽固性心力衰竭患者中的应用及对患者预后的影响。方法 30例顽固性心力衰竭患者经常规药物治疗效果不佳后接受CRRT治疗,观察治疗前后患者的心率、血压、呼吸频率、尿量、肺部口罗音、肝颈静脉回流征和双下肢水肿等的变化,并判断心功能的改变;测定治疗前、后左心室射血分数、左心室舒张末期内径、心胸比、肾功能及电解质等。结果大部分患者经过CRRT治疗后,症状与心功能分级明显改善,心胸比减少,左室内径缩小,左心室射血分数显著增加,心功能从Ⅳ级提高到Ⅱ、Ⅲ。结论通过CRRT能持续、缓慢、平稳地清除水分及溶质,较好地维持血流动力学的稳定性,对顽固性心力衰竭的治疗有显著效果。 Objective To investigate the efficacy of continuous renal replacement therapy(CRRT) on patients with intractable heart failure(IHF).Methods 30 cases with IHF were treated by CRRT.The clinical manifestations and the laboratory parameters including heart rate,respiratory rate,blood pressure,urine volume,hepatojugular reflux sign,edema of lower extremity,cardiac functional classification,left ventricle ejection fraction(LVEF),left ventricular end diastolic dimension(LVEDd),cardiothoracic ratio(CTR),electrolyte,blood urea nitrogen(BUN) and serum creatinine(Scr) were observed before and after CRRT treatment.Results After CRRT,the clinical symptoms and cardiac function of the majority of the patients were improved.The left ventricle ejection fractions were increased,and heart function improved from Class Ⅳ to Ⅱ~Ⅲ.Conclusion CRRT can keep hemodynamics stable during removing excess water and it is an effective method to treat intractable heart failure.
出处 《实用临床医药杂志》 CAS 2011年第1期74-75,78,共3页 Journal of Clinical Medicine in Practice
关键词 连续性肾脏替代疗法 顽固性心力衰竭 血液过滤 continuous renal replacement therapy intractable heart failure blood filtration
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