5Lorente I., Lorenzo L, M artin MM, et al. Meropenem by continuous versus intermittent infusion in ventilatoPassociated pneumonia due to Gramnegative bacilli[J].Ann Pharmacother, 2006,40(2) :219 -223.
7Lomaestro BM, Drusano GI.. Pharmacodynamic evaluation of extending the administration time of meropenem using a Monte Carlosimulation [J]. Antimicrob Agents Chemother, 2005, 49 (1) : 461-463.
8Cipolle RJ, Strand LM, Morley PC. Pharmaceutical Care Practice: the Clinician' s Guide[M].2nd ed.New York: Mc- Graw-Hill, 2004:1.
9E1 Mouedden M, Laurent G, Mingeot-Leclercq MP, et al. Ap- optosis in renal proximal tubules of rats treated with low doses of aminoglycosides E J ]. Antimicrob Agents Chemother, 2000, 44 ( 3 ) :665-675.