摘要
目的观察延迟经皮冠状动脉支架植入术（PCI）对急性心肌梗死患者左心室重构及心脏事件的影响。方法将经药物治疗后病情稳定的急性心肌梗死患者分成延迟PCI治疗＋药物治疗组（A组）和单纯药物治疗组（B组）。在入院即刻、7d和180d采用超声心动描记术评价左心室整体功能，并进行比较。结果A组患者行PCI术后180d左心室射血分数（LVEF）及左心室舒张末期内径（LVESd）、左心室收缩末期内径（LVESd）等指标（58．49±6．65、45．20±5．15、32．04±8．55）与术后7d（51．69±5．00、47．77±3．10、37．57±5．92）相比，差异有统计学意义（P〈O．05），与B组术后180d（53．16±5．92、46．20±4．60、35．40±7．40）比较，差异均有统计学意义（均P〈0．05）；PCI术后7d两组上述指标比较，差异无统计学意义（均P〉0.05）。讨论延迟PCI有助于防止左心室重构．改善心功能，使心脏不良事件明显下降。
Objective To evaluate effect of delayed percutaneous coronary intervention （PCI） on left ventricular（LV） remodeling and function after acute myocardial infarction （AMI）. Methods Sixty-seven patients with AMI, ineligible for primary PCI, were treated with delayed PCI plus medical therapy （group A, n=35） or only medical therapy （group B, n=32）. The LV dimension and function were evaluated by echocardiography at the moment of admission, 7 days and 180 days later. Results LV diastolic and systolic dimensions were significantly less, and LV ejection fraction was significantly higher at 180 days than at 7 days in group A, and than that in group B. No significant difference of these parameters was observed at 7 days between two groups. Conclusion Delayed PCI may be benefit to LV remodeling and function after AMI.
出处
《心电学杂志》
2011年第1期11-13,共3页
Journal of Electrocardiology(China)
关键词
急性心肌梗死
延迟PCI
左心室重构
心脏事件
Acute myocardial infarction
Delayed PCI
Left ventricular remodeling
Cardiac events
