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2009年甲型H1N1流感患者临床特点的研究 被引量:1

Clinical Features of the Hospitalized Patients with 2009 H1N1 Influenza
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摘要 目的调查2009年甲型H1N1流感患者的临床特点。方法通过调查2009年11月至2010年2月符合流感疑似病例收治入院的136例患者,明确2009甲型H1N1流感组,季节性甲型流感组和非流感组的人口学情况,肺炎发生的差异,危重症发生的差异,以及实验室检测参数的差异,筛选出需要住院的流感疑似患者发生肺炎的危险因素。结果 2009甲型H1N1流感发病年龄更年轻(36±17岁);孕妇的构成比(42.2%)高于其他组;发生肺炎的构成比(51.11%)高于其他组;病死1例。D-二聚体、AST、LDH异常增加的构成比明显大于其他发热患者。结论甲型H1N1流感的易感人群是年轻人和孕妇。甲型H1N1流感是发生肺炎的危险因素,容易并发肺炎和呼吸衰竭,及引起血凝系统、骨骼肌、心肌的损害。 Objective To explore the clinical features of the hospitalized patients with 2009 H1N1 influenza.Method We evaluated 136 hospitalized patients with suspected 2009 H1N1 influenza during November 2009 and February 2010.Result We found 45 hospitalized patients with H1N1 influenza,include 19 Pregnant women(42.2%);21 pneumonia(51.11%);1 died(2.2%);Compared with other fever patients,the constituent ratio of pregnant women and pneumonia are all obviously increased;the constituent ratio of abnormal value of D-Dimer、AST、LDH are all obviously increased;Logistic regression analysis displaied the risk factors for pneumonia is 2009 H1N1 influenza.The mean age of the 2009 H1N1 influenza patients is 36±17.Conclusion The susceptible population in the 2009 H1N1 influenza is younger and pregnant women;2009 H1N1 influenza is the risk factors for pneumonia;2009 H1N1 influenza can cause damage in the coagulative and fibrinolytic systems and damage in the skeleton muscles、heart muscles.
出处 《临床肺科杂志》 2011年第3期336-337,共2页 Journal of Clinical Pulmonary Medicine
关键词 2009年甲型H1N1流感 临床特点 肺炎 危险因素 2009 H1N1 influenza clinical features pneumonia risk factors
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参考文献6

  • 1Bin Cao,Li X W,Yu Mao,et al,Clinical Features of the Initial Ca-ses of 2009 Pandemic Influenza A(H1N1) Virus Infection in China[J].N Engl J Med,2009,361:2507-17.
  • 2Seema,Laurie,Anna et al.Hospitalized Patients with 2009 H1N1 Influenza in the United States,April-June 2009[J].N Engl J Med,2009,361:1935-44.
  • 3Jamieson DJ,Honein MA,Rasmussen SA,et al.H1N1 2009 influ-enza vims infection during pregnancy in the USA[J].Lancet,2009,374:451-8.
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