摘要
目的观察布洛芬混悬液治疗小儿发热的临床疗效与安全性。方法 203例高热患儿随机分为观察组102例和对照组101例。观察组给予布洛芬混悬液治疗;对照组给予对乙酰氨基酚混悬剂治疗。观察2组疗效及安全性。结果 观察组退热效果评分为(2.88±0.17)分高于对照组的(2.62±0.37)分,总有效率98.0%高于对照组的91.1%,差异均有统计学意义(P<0.05)。2组治疗后体温均较治疗前降低,且观察组不同时段的退热效果均优于对照组,差异有统计学意义(P<0.01)。结论布洛芬混悬液退热疗效好,作用强,持续时间长,口服方便,不良反应少,可作为儿科退热的常用药物之一。
Objective To observe the clinical efficacy and safety of ibuprofen suspension in the treatment of fever in children.Methods 203 children with high fever were randomly divided into observation group of 102 and control group of 101.The observation group was treated with ibuprofen suspension,while the control group was treated with paracetamol suspension.The efficacy and safety of 2 groups were observed.Results The effect score of reducing fever of the observation group was（2.88±0.17）higher than（2.62±0.37）of the control group;The total effective rate of the observation group was 98.0% higher than 91.1% of the control group.All the differences above were statistically significant（P0.05）.After treatment,the temperature of children in both groups was reduced,and at different periods of time,the effect of reducing fever of the observation group was better than that of the control group,and the differences were statistically significant（P0.01）.Conclusion Ibuprofen suspension has good efficacy on reducing fever,which is of strong action,long lasting time,convenient oraly taking and less adverse reaction,so it can be one of the usual drugs for reducing fever in the department of pediatrics.
出处
《临床合理用药杂志》
2011年第2期21-22,共2页
Chinese Journal of Clinical Rational Drug Use
