摘要
目的比较干预组和对照组学校伤寒、副伤寒发病率,为降低和控制学校伤寒、副伤寒的发生提供依据。方法以广西伤寒副伤寒高发地区全州县为项目现场。采用整群分层抽样方法确定干预组和对照组学校,建立以固定人群为基数、病原学为确诊依据的前瞻性监测系统进行伤寒、副伤寒监测,为期16个月。结果甲型副伤寒发病39例,伤寒发病0例,其中对照学校甲型副伤寒发病数33例,发病率为185.0/10万,干预组学校发病6例,发病率为30.7/10万。对照组学校发病率显著高于干预组学校(P=0.000)。由个体/村诊所、乡镇卫生院收集标本采集数和阳性标本数,分别占74.2%和66.7%。单份血标本W idal试验敏感度仅为32.3%,假阴性率为67.6%。结论在实施干预措施后,干预组学校的伤寒、副伤寒发病率比对照组学校有明显下降。
Objective To compare the typhoid and paratyphoid incidences between intervention schools and control schools, and to provide evidence for reducing and controlling the prevalence of school typhoid ＆ paratyphoid. Methods Cluster-randomized stratified controlled methods was used to determine intervention schools and control schools. A prospective population-based, culture confirmed typhoid and paratyphoid surveillance system was established to monitor the diseases. Results Total 39 S. paratyphi A infections and 0 S. typhi infection were reported. Of which, 33 S. paratyphi A infections were reported from control schools and incidence reached 185.0 per 100 000, while 6 S. paratyphi A infections were reported from intervention schools and incidence was 30.7 per 100 000. The incidence in controls was significantly higher than interventions （P = 0. 000 ）. Most blood samples and confirmed cases were collected and reported by village clinics and township Health Centers which were 74.2% and 66.7% respectively. The sensitivity and false negative rate was 32.3% and 67.6% respectively. Conclusion After implementation of intervention program, the typhoid and paratyphoid incidence in intervention schools has decreased significantly than control schools.
出处
《中国学校卫生》
CAS
北大核心
2011年第1期69-71,共3页
Chinese Journal of School Health
基金
中国疾病预防控制中心合作项目
广西卫生厅重点项目(重200612)
关键词
伤寒
副伤寒
患病率
学生
Typhoid fever
Paratyphoid fever
Prevalence
Students
