摘要
为探讨纳洛酮对难治性精神分裂症患者的治疗效果,对32例难治性患者在原来抗精神病药不变的情况下合并纳洛酮肌注,进行2周自身对照研究,结果显示,以BPRS和PANSS评定临床有效率分别为30%和26.7%,对BPRS中幻听、关心身体健康症状的临床有效率分别为73.3%和40%。除2例因出现高血压而中断治疗外,未见其它严重副反应。揭示纳洛酮对难治性精神分裂症、尤其是伴有幻听症状者,有较好的治疗效果。
To study the effect of naloxone inrefractory schizophrenia patients, Method: 32 cases weremuscle injected naloxon, keeping the original neuroleptics not inhibited. It lasted for two weeds to make a self-control study. Results: Assessed by BPRS and PANSS, the effectual rate was 30% and 26. 7% seperately. The effects for hallucfination, caring physical healty by BPRS was 73. 3% and 40%seperately. Dtherserious side-effect weren't found except two cases breaking off tor bypertension. Conclusion:It suggests that naloxone has a better effect for refractoryschizophrenia,especially for those with hallucianation
出处
《健康心理学杂志》
1999年第3期287-290,共4页
Health Psychology Journal