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辛伐他汀预防慢性心力衰竭患者下肢深静脉血栓形成的临床观察 被引量:7

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摘要 目的观察辛伐他汀对慢性心力衰竭患者下肢深静脉血栓形成的预防作用。方法将126例首次就诊的慢性心力衰竭患者随机分成辛伐他汀治疗组63例和常规治疗组63例。辛伐他汀治疗组在常规治疗的基础服辛伐他汀20 mg,1次/晚,治疗12周后监测患者下肢深静脉血栓形成及心功能情况。结果辛伐他汀治疗组出现下肢深静脉血栓3例(4.8%),常规治疗组17例(27.0%),差异有统计学意义(P<0.05)。辛伐他汀治疗组治疗后血栓前状态(PTS)标志物水平明显低于常规治疗组,差异有统计学意义(P<0.05)。结论辛伐他汀能有效预防慢性心力衰竭患者下肢深静脉血栓形成。
出处 《重庆医学》 CAS CSCD 北大核心 2011年第4期376-377,共2页 Chongqing medicine
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