摘要
以L-(+)-酒石酸和吡啶甲酸为原料,经酯化,缩合、还原、DCC-DMAP催化酯化等反应合成了3个新型手性多齿配体——(4R,5R)-1,3-二氧戊环-2-苯基-4,5-二吡啶羧酸酯(5a～5c),其结构经1H NMR,13C NMR,IR和MS表征,并通过高斯软件HF/6-31G模拟了5a可能的分子结构。
Three novel chiral polydentate ligands,（4R,5R）-1,3-dioxolane-4,5-bis-pyridinecarboxylic esters（5a～5c）,were synthesized from L-（＋）-tartaric acid and pyridinecarboxylic acids by a four-step reaction of esterification,condensation,reduction and DCC-DMAP catalytic esterification.The structures were characterized by 1H NMR,13C NMR,IR and MS.The probable molecular structure of 5a was imitated by molecular simulation software Gaussian HF/6-31G.
出处
《合成化学》
CAS
CSCD
北大核心
2011年第1期81-84,共4页
Chinese Journal of Synthetic Chemistry
基金
江苏省精细石油化工重点实验室开放课题资助项目(ICF0503)
关键词
手性多齿配体
吡啶羧酸酯
吡啶甲酸
合成
chiral polydentate ligand
pyridinecarboxylic ester
pyridine-fomic acid
synthesis
