摘要
目的:探讨中药益气、活血、散结法配合介入化疗在晚期NSCLC治疗中的价值和规律。方法:对54例NSCLC患者介入化疗后分时限给予益气、活血、散结法治疗(A组),并与30例益气、活血、散结并用(B组)进行比较。结果:两组近期疗效相似,A组有效率为552%、B组为583%(P>005),但6个月转移率,A、B两组分别为74%、267%,1年生存率A、B两组分别为851%、677%(P<005),中位生存期分别为161个月和138个月。免疫功能A组高于B组。结论:益气、活血、散结分时限给药能减少6个月的转移率,提高机体免疫力,延长中位生存期及远期生存率。
Objective:To observe the effect of Chinese medicinal herbs of strengthening vital energy(SVE),activating blood circulation (AB) and dispersing tumor (DT) combined with interventional chemotherapy on advanced non small cell lung cancer(NSCLC).Methods:Comparing the therapeutic effects of two treatment regimens on 58 advanced NSCLC patients who were treated after interventional chemotherapy with SVE,AB and DT in different periods (A group),and 30 cases treated after interventional chemotherapy with SVE and AB and DT at the same time (B group).Results:The effective rates were 55 2% in A group and 58 3%in B group .There were no significant differences between A group and B group accor ding to the short term results ( P <0 05).But the metastasis rates in 6 months were 7 4% and 26 7% in A and B respectively( P <0 05).The one year and more survival rate was 85 1% in A and 67 7% in B( P <0 05). Median survival time for A and B group were 16 1 and 13 8 months respectively.A group were better than B group in improving patients immunological function.Conclusion:The regimen of strenthening vital energy,activating blood circulation and dispersing tumor at different periods can reduce the six month metastasis rate,improve the patients immnological competence and prolong the median survival time and long term survical rate.
出处
《中国中西医结合外科杂志》
CAS
1999年第4期203-206,共4页
Chinese Journal of Surgery of Integrated Traditional and Western Medicine