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慢性阻塞性肺疾病与重叠综合征患者肺功能及睡眠结构分析 被引量:19

Analysis and sleep structure in chronic obstructive pulmonary disease and overlap syndrome
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摘要 目的:探讨慢性阻塞性肺疾病(COPD)与重叠综合征(OS)患者肺功能及血气分析特点以及睡眠结构特点并分析其临床意义。方法:选择45例COPD稳定期患者作为研究对象,经多导睡眠监测(PSG)后按结果分为单纯COPD组29例,OS组16例,测定并分析其肺功能及血气分析。结果:OS组肺功能受损尤其气流阻塞较COPD组严重;与COPD组对比,OS组SaO2A,SaO2L,TST,PLMI,S3+4,REM显著降低(P<0.01)。SLT90%,TL,TA,AI和S1+2显著升高(P<0.01)。结论:OS较COPD更易缺氧,并易导致严重肺功能损害及其他并发症。 Objective:To investigate the characteristics of pulmonary function,blood gas and sleep structure in the patients with chronic obstructive pulmonary disease(COPD) and overlap syndrome(OS),and to analyze their clinical significance.Methods:45 cases of stable stage of COPD were selected as study subjects.According to the results after monitoring by polysomnography(PSG),the patients were divided into the simple COPD group(29 cases) and the OS group(16 cases).The lung function and blood gas were detected and analyzed in the two groups.Results:The impairment of pulmonary function,especially the airflow obstruction in the OS group was more severe than that in the simple COPD group;compared with the COPD group,SaO2A,SaO2L,TST,PLMI,S3+4 and REM in the OS group decreased significantly(P0.01).SLT 90%,TL,TA,AI and S1+2 significantly increased(P0.01).Conclusion:OS is easier to hypoxic than COPD,and easy to cause serious damage of lung function and other complications.
作者 周晖 唐万平
出处 《现代医药卫生》 2011年第1期7-8,共2页 Journal of Modern Medicine & Health
关键词 慢性阻塞性肺疾病 重叠综合征 睡眠结构 肺功能 Chronic obstructive pulmonary disease Overlap syndrome Sleep structure lung function
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