摘要
目的研究加味保元汤对束缚应激小鼠巨噬细胞吞噬功能的影响。方法８０只小鼠随机等分成正常组、应激组、应激加药组和应激加水组，用巨噬细胞体内吞噬法，测其吞噬率及吞噬指数。结果应激组与正常组比较，应激组吞噬率及吞噬指数明显降低（Ｐ＜０．０１）；应激加药组与应激组比较，应激加药组吞噬率及吞噬指数明显升高（Ｐ＜０．０１）；应激加水组与应激组比较，吞噬率及吞噬指数均无明显改变（Ｐ＞０．０５）；应激加药组与应激加水组比较，应激加药组吞噬率及吞噬指数明显升高（Ｐ＜０．０１）；应激加药组与正常组比较，吞噬率无明显改变（Ｐ＞０．０５）。结论加味保元汤对束缚应激小鼠巨噬细胞吞噬功能具有保护作用。
Objective To study the effect of Baoyuan Tang on
macrophage phagocytosis of mice by restraint stress. Method Eighty mice were divided
randomly into nomal group,stress group,stress group adding Baoyuan Tang and stress group
adding water to detect the phagocytic rate and phagocytic index by means of phagocytosis
within body. Results Both phogocytic rate and phagocytic index of stress group decreased
highly compared with that of nomal group;(P<0. 01) ; both phagocytic rate and phagocytic
index of stress group adding Baoyuan increased significantly compared with that of stress
group (P< 0. 01) ; between stress group adding water and stress group, both phagocytic rate
and phagocytic index had no changes (P>0.05); phagocytic rate and phagocytic index of stress
group adding Baoyuan increased significantly compared with thaf of stress group adding water
(P< 0. 01) ; between stress group adding Baoyuan and nomal group, phagocytic rate had no
changed (P>0.05). Conclusion Baoyuan Tang plays a protective role on macrophage
phagacytosis in mice by reslraint stress.
出处
《中国行为医学科学》
CSCD
1999年第2期99-101,共3页
Chinese Journal of Behavioral Medical Science
