摘要
为探讨充血性心力衰竭（ＣＨＦ）患者血清甲状腺激素水平的变化及其临床意义，用放免法测定了５２例ＣＨＦ患者及２８例正常人（对照组）血清甲状腺激素水平。结果显示：ＣＨＦ组血清三碘甲状腺原氨酸（Ｔ３）为１．５２±０．７６ｎｍｏｌ／Ｌ，较对照组（２．０５±０．８７ｎｍｏｌ／Ｌ）显著降低（Ｐ＜０．０５），血清反三碘甲状腺原氨酸（ｒＴ３）为０．８９±０．３７ｎｍｏｌ／Ｌ，较对照组（０．６２±０．２５ｎｍｏｌ／／Ｌ）显著升高（Ｐ＜０．０５），且心衰程度越重，变化越明显；Ｔ３与心衰程度呈负相关，ｒＴ３与心衰程度正相关。结果提示：血清Ｔ３、ｒＴ３水平的改变可作为判断ＣＨＦ严重程度的指标之一。
In order to explore the relationship between congestive heart failure (CHF) and serum thyroxine, we assayed serum thyroxine level in 52 patients with CHF and 28 normal persons by means of radioimmunoassay (RIA). The results showed that triiodothyronine reduced and reverse triiodothyronine elevated significantly in the patients compared with the normal (P<0.05). The more severe heart failure developed, the more obvious changes of the hormones were observed. The results suggest that the alterations of serum thyroid level may be used as an index of the severity of heart failure.
出处
《华西医科大学学报》
CSCD
1999年第2期196-197,201,共3页
Journal of West China University of Medical Sciences
