摘要
目的观察大剂量甲基泼尼松龙冲击治疗重症特发性血小板减少性紫癜（ＩＴＰ）的疗效。方法甲基泼尼松龙每天静滴２０～３０ｍｇ·ｋｇ－１，连续３天，继以泼尼松维持，治疗５５例患者。结果５５例患者出血症状得到良好的控制，血小板升高，完全反应率为２５４５％，部分反应率为４５４５％，总有效率为７０９０％；血小板升高时间为４～１４天。结论大剂量甲基泼尼松龙冲击治疗是重症ＩＴＰ患者较安全有效的方法。
Objective In order to determine the curative effect of high dose methylprednisolone (HDMP) in treatment of severe patients with idopathic thrombocytopenic purpura (SITP). Methods 50 patients with SITP were intravenously given methylprednisolone by 20～30 mg·kg -1 ·d -1 3 days and then adopted consolidation therapy of prednisone. Results There was a good curative effect in alleviating the spontaneous bleeding symptoms in all cases, and the number of platelets increased in some patients, The complete response rate was 25 45% and the partial response rate 45 45%, and the total response rate 70 90%. In general, the number of platelets would increase after the 4th～14th day of treatment. Conclusion Curative effect of HDMP in treating the patients with SITP is safe and effective.
出处
《安徽医科大学学报》
CAS
1999年第2期123-124,共2页
Acta Universitatis Medicinalis Anhui
关键词
紫癜
血小板减少性
甲基泼尼松龙
冲击疗法
purpura, thrombocytopenic, idopathic/drug ther
methylprednisolonese/admin and dosage
critical illness
