摘要
目的探讨术中急性中度等容血液稀释对小肠血流灌注和氧输送、氧耗的影响。方法１５只雄性家猫，用多聚明胶将血红蛋白稀释至８４ｇ／Ｌ，在血液稀释前后分别测定肠系膜上动脉血流量，肠系膜上静脉血乳酸量，作肠系膜上动脉、静脉血气分析，分别计算血液稀释前后的小肠氧输送量、氧耗量和氧摄取率。结果血液稀释后肠系膜上动脉血流量及小肠氧耗量较稀释前有显著意义的升高（Ｐ＜００５），小肠氧输送量和小肠氧摄取率无显著性变化（Ｐ＞００５）。结论用胶体进行急性中度等容血液稀释时可使肠系膜上动脉血流灌注量明显增加，从而维持正常的小肠氧输送量，不会造成肠粘膜的缺血。
Objective To study the effects of moderate acute normovolemic hemodilution
on the intestinal blood perfusion and oxygen supply in cats. Methods 15 domestic male cats
were hemodiluted with Haemoccel. HR, MAP, lactate concentration in superior mesenteric vein
(LAC), superior mesenteric artery blood flow (SMABF), superior mesenteric artery and venous
blood gas analysis were recorded and the intestinal oxygen delivery (DO2), oxygen
consumption (VO2) and oxygen extraction (EO2) were calculated before and after hemodilution.
Results SMABF increased obviously (P<005), intestinal DO2 and EO2 did not change (P>005)
but VO2 increased (P<005), and LAC in superior mesenteric vein did not increase. Conclusions
Moderate acute normovolemic hemodilution with Haemaccel do not alter intestinal oxygen
delivery by increasing the superior mesenteric blood flow.It means that intestinal mucosa
ischemia does not happen during moderate acute normovolemic hemodilution.
出处
《中华外科杂志》
CAS
CSCD
北大核心
1999年第5期306-308,共3页
Chinese Journal of Surgery
关键词
血液稀释
微循环
小肠
氧消耗
氧输送
HemodilutionMicrocirculationIntestinal,smallOxygen consumption
