摘要
目的：探讨放疗对局限期和广泛期小细胞肺癌化疗疗效的影响。方法：用寿命表法和ＬｏｇＲａｎｋ法分析比较６１例化疗加放疗（化放组）和同期４６例单纯化疗（单化组）小细胞肺癌的生存率。结果：化放组病人１、３、５年生存率分别为７０５％、２５４％和１２９％，而单化组分别为４０７％、２６％和２６％，两组比较有显著差异（Ｐ＜００１）。在局限期病人中，化放组１～５年生存率明显高于单化组（Ｐ＜００２５），而在广泛期病人中，化放组１～５年生存率与单化组无差异（Ｐ＞００５）。结论：放疗能提高局限期小细胞肺癌化疗后的生存率，而对广泛期病人的生存率无影响。
bjective: A retrospective analysis was performed to
study the influence of radiotherapy on the effectiveness of chemotherapy in the patients with
limited or extensive stage SCLC. Methods: Survival rates were analyzed and compared by life
table and LogRank test between 61 patients with SCLC treated with chemoradiotherapy and 46
patients with chemotherapy alone. Results: The 1,3,5year survival rates of the patients with
SCLC were 705%,254%,129%respectively in chemoradiotherapy group and
407%,26%,26%respectively in chemotherapy only group, showing a significant difference
between the two groups (P< 001). The 15year survival rates of patients with limited stage SCLC
in chemoradiotherapy group were higher than those in chemotherapy group (P< 0025), but there
was no difference between the two groups for patients with extensive stage SCLC ( P>005).
Conclusion: The survival rates can be increased with chemoradiotherapy for patients with
limited stage SCLC, but there was no difference for patients with extensive stage SCLC.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1999年第3期330-331,346,共3页
Chinese Journal of Cancer
