摘要
目的:评价不同麻醉方法下支气管肺泡灌洗术治疗肺部感染的效果。方法:30例肺部感染患者随机分为两组,A组采用单腔气管插管全麻,术中行双肺机械通气;B组采用双腔气管插管全麻,术中行单肺机械通气。观察比较两组患者灌洗前及灌洗结束后心率(HR)、平动脉压(MAP)、氧饱和度(SpO2),并检测血气,记录pH、PaO2、PaCO2,及灌洗时间、手术时间、灌洗液量的变化情况。结果:灌洗前后A组及B组患者生命体征HR及MAP的变化无明显差异(P>0.05)。灌洗后PaO2及pH值B组较A组有明显提高(P<0.05),SpO2和PaCO2在两组间未见明显统计学差异(P>0.05);而灌洗液量B组较A组明显增加(P<0.05),灌洗时间B组较A组增加,手术时间明显减少(P<0.05)。结论:全麻下行双腔管气管内插管双肺隔离后单肺通气进行支气管肺泡灌洗术是安全、效果明显的麻醉方法。
Objective:To investigate the effects of different anaesthetic techniques on Bronchoalveolar Lavage in therapy of pulmonary infection. Methods:30 patients undergoing bronchoalveolar lavage (BAL) were divided in to 2 groups randomly. Total - lung ventilation (TLV) was used in group A during general anesthesia, while one - lung ventilation(OLV) was used in group B. The heart rate, mean arterial pressure, pulse oxygen saturation and blood gas analysis were monitored before and after BAL. The lavage time, operation time and volumes of bronchoalveolar lavage fluid were also recorded and compared. Results : No difference of HR or MAP was observed between 2 groups ( P 〉 0.05 ). After BAL, PaO2 and pH in group B were higher compared with A group ( P 〈 0.05 ) , while there was no significant difference of SpO2 or PaCO2 between 2 groups ( P 〉 0.05 ), The volumes of hronchoalveolar lavage fluid and lavage time increased in group B compared with group A . Meanwhile, the operation time in group B was much less than that of in group A ( P 〈 0. 05 ). Conclusion: One - lung ventilation together with general anesthesia is a safe and effective approach during BAL.
出处
《现代肿瘤医学》
CAS
2011年第2期347-349,共3页
Journal of Modern Oncology
关键词
支气管肺泡灌洗
肺部感染
麻醉
bronchoalveolar Lavage
pulmonary infection
anesthesia .